Special Issues

Special Issue Title: Uterus Transplantation: current evidences, open questions and future directions

· Print Special Issue Flyer

· Deadline for manuscript submissions: 30 September 2021

Special Issue Editor

Guest Editor

Prof. Paolo Scollo

Division of Gynecology and Obstetrics, Maternal and Child Department, Cannizzaro Hospital, Catania, Italy

Website | E-Mail

Interests: Gynecologic oncology; Uterus transplantation

Prof. Mats Br?nnstr?m

Department of Obstetrics and Gynecology, University of Gothenburg, G?teborg, Sweden

Website | E-Mail

Interests: Ovulation mechanisms; Effects of prophylactic oophorectomy; Uterus transplantation; Bioengineered uterus and ovary; Ovarian cryopreservation

Dr. Giuliano Testa

Baylor Scott & White Transplant Services, Dallas, United States

Website | E-Mail

Interests: Abdominal transplant; Uterine transplant

Special Issue Information

Dear Colleagues,

Uterus transplantation (UTx) is now a real opportunity for women affected by absolute uterine factor infertility (UFI) to get pregnancy. UFI, either congenital or acquired, affects 1 in 500 fertile-aged women. The most frequent congenital reason for UFI is MRKH syndrome. 

UTx represents a special event in the field of transplantation: it’s a temporary transplant, non-lifesaving and involving several parts. There are two valid options for donation: living or deceased. In fact, it has been highlighted that both options are possible to deliver a child. Scientific researches about Utx had involved many continents in the world (America, Europe and Asia), to date, several groups have performed more than 70 UTx procedures in total, resulting in the delivery of more than 30 newborns according to the available literature and media. The first baby after UTx from living donor was born in Sweden by Br?nnstr?m et al. in September 2014. First live birth after Utx in the United States was published in 2018 by Testa et al. After the first live birth after Utx from deceased donor in Brazil in 2017, research about Utx from brain dead donor was performed in many countries, including USA, Chech Republic and Italy. 

However, UTx is still in the experimental stage and there are many medical, surgical, psychological and ethical issues to be resolved. 

It’s necessary to investigate about comparison between live and deceased donor trial in order to understand if a better option exists or both options are equally valid. Issues about surgical retrieval (open, laparoscopy and robotic), graft explantation with vascular connessions and alternative drainage outflow (ovaric vein) are highly debated. There are also many sentences to be answered about psychological assessment, considered data of literature about the importance of psycological support in the patients affected from UFI and particulary MRKH syndrome. 

The global emergency from COVID-19 pandemic determined almost 2 million of deaths worldwide, damaged in many cases the ordinary medical assistence in the last year, overshadowing not essential services and making difficult for people to access in the hospitals for Utx.

The aim of this Special Issue is to resume the current state-of-art about UTx, discussing debated issues in UTx, and to develop new ideas for the future.

Prof. Paolo Scollo, Prof. Mats Br?nnstr?m and Dr. Giuliano Testa

Guest Editors


Manuscript Submission Information

Manuscripts should be submitted online at https://ceog.imrpress.org by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Clinical and Experimental Obstetrics & Gynecology is an international peer-reviewed open access quarterly journal published by IMR Press.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is $1250. Submitted papers should be well formatted and use good English.


Uterus transplantation; Deceased donor; Live donor; MRKH syndrome; Surgery; Psychological

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