Endometriosis, adenomyosis, and uterine fibroids are some of the most frequent benign gynecological conditions. These gynecological diseases have a broad spectrum of manifestations; in fact, they can be asymptomatic in some patients or cause severe symptoms (such as pelvic pain, heavy menstrual bleeding, and infertility) that significantly affect the quality of life, working efficiency, and sexuality.
Transvaginal ultrasonography is the first-line investigation for the diagnosis of these conditions. However, the diagnostic performance of transvaginal ultrasonography is dependent on the experience of the ultrasonographer. Magnetic resonance imaging may be used to confirm the diagnosis and provide a better definition of these diseases' characteristics.
These conditions develop in an estrogen-dependent fashion; therefore, they are infrequent before the menarche and, usually, regress after menopause. Hormonal therapies that suppress circulating ovarian hormones can improve the symptoms caused by these conditions. However, hormonal therapies do not “cure” these diseases, and symptoms usually recur when the treatment is discontinued.
Surgery may improve the symptoms caused by endometriosis, adenomyosis, and uterine fibroids. It should be performed by minimally invasive techniques such as hysteroscopy, laparoscopy, and robotic surgery. Compared with traditional laparotomy, these surgical techniques decrease postoperative pain and improve postoperative recovery. The choice to perform a surgical procedure is based on several variables, including characteristics and intensity of symptoms, age of the patients, desire to preserve fertility, and conceive comorbidities.
Over the last ten years, the management of endometriosis, adenomyosis, and uterine fibroids has mostly changed. The better knowledge of the molecular pathways involved in the pathogenesis of these conditions has led to the development of new drugs to treat these conditions. Also, new diagnostic tools and surgical instruments have improved the management of these diseases.
This special issue aims to provide an update on the diagnosis and management of endometriosis, adenomyosis, and uterine fibroids.
Prof. Simone Ferreroa nd Dr. Fabio Barra
Manuscript Submission Information
Manuscripts should be submitted online at https://ceog.imrpress.org by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on theInstructions for Authorspage. Clinical and Experimental Obstetrics & Gynecology is an international peer-reviewed open access quarterly journal published by IMR Press.