Special Issues

Special Issue Title: CoVID-19 in OB/GYN

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· Deadline for manuscript submissions: 31 May 2021

Special Issue Editor

Guest Editor

Prof. Romolo Di Iorio

Department of Medico-Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy

Website | E-Mail1 | E-Mail2

Interests: CoVID-19; SARS-CoV-2; pregnancy; gynaecologic oncology; human reproduction; fertility and sterility

Prof. Paola Bianchi

Department of Medico-Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy

Website | E-Mail

Interests: CoVID-19; SARS-CoV-2; pregnancy; gynaecologic oncology; human reproduction; fertility and sterility

Special Issue Information

Dear Colleagues,

Between the end of 2019 and the beginning of 2020, a novel coronavirus, named SARS-CoV-2 (Severe Acute Respiratory Syndrome - Coronavirus 2) was identified and correlated to the new emerging viral pneumonia, consequently named CoVID-19 (Coronavirus Disease 2019).

A worldwide public health response has ensued to address the impact of the CoVID-19 pandemic. Unfortunately, the almost exclusive emphasis on high-risk populations, including older people and people with serious underlying medical conditions, resulted in a relative neglect of the specific risks and needs of other populations such as women, when in fact the CoVID-19 pandemic is affecting various areas of health care, including reproductive health.

The pandemic is associated with decreased desire for pregnancy, decreased use of contraception, and increased menstrual disorders. Fertility treatments have been postponed in order to support the healthcare system by avoiding placing it under increased pressure. In addition, an indirect effect of the virus on gametes and embryos during their manipulation cannot be ruled out.

In the field of gynaecologic oncology, from CoVID-19 pandemic outbreak, the highest priority is to achieve the maximum benefit from less demanding procedures. Extensive procedures should be avoided, in order to reduce the in-hospital spread of the virus. Nevertheless, surgery for some gynaecologic pathologies cannot be postponed.

CoVID-19 is associated with a systemic inflammatory response with activation of coagulation in symptomatic patients. The possibility of coagulopathies in peri- and post-menopausal women taking oestrogens makes it necessary to consider antithrombotic strategies.

Due to the physiological changes in the immune and cardiopulmonary systems, pregnant women are more likely to develop severe illness after infection with respiratory viruses. At the beginning of the epidemic, the possibility that CoVID-19 may adversely influence pregnancy was raised and guidelines were issued. More recently, a few systematic reviews have shown that, in most cases, in pregnancies complicated by CoVID-19 infection, foetal and neonatal outcomes appear good, although information gathered so far only include pregnant women infected in their third trimester. Furthermore, pregnancy-related complications appear to vary depending on settings and screening strategies for SARS-CoV-2 identification (universal, based on epidemiological risk, or on symptoms).

The goal of this special issue is to provide additional data, both original articles and comprehensive reviews, about women’s health in CoVID-19 era to develop effective preventive and clinical strategies.

Prof.Romolo Di Iorio, MD, PhD

Prof. Paola Bianchi, MD

Guest Editor


Manuscript Submission Information

Manuscripts should be submitted online at https://ceog.imrpress.org by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Clinical and Experimental Obstetrics & Gynecology is an international peer-reviewed open access quarterly journal published by IMR Press.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is $1250. We normally offer a discount about 30% (APC: $850) to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.


CoVID-19; SARS-CoV-2; pregnancy; gynaecologic oncology; human reproduction; fertility and sterility

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Consequences of SARS-CoV-2 disease on maternal, perinatal and neonatal outcomes: a retrospective observational cohort study
Sahar H. Abdulghani, Lana A. Shaiba, Mahdya A. Bukhari, Muhab M. Hindi, Shaikh A. Hussain, Adnan A. Hadid
Clinical and Experimental Obstetrics & Gynecology    2021, 48 (2): 353-358.   DOI: 10.31083/j.ceog.2021.02.2361
Abstract26)      PDF(pc) (184KB)(7)       Save

Novel coronavirus disease 2019 (COVID-19) continues to affect pregnant women with concerns for adverse maternal and fetal outcomes and is rapidly spreading throughout many countries since it was first reported in China on 31 December 2019. The aim of this study is to describe characteristics, maternal and fetal outcomes among mothers with confirmed maternal SARS-CoV-2 infection. This study presents a retrospective observational cohort study of 62 test-positive cases of coronavirus disease 2019 that presented at an affiliated tertiary university medical city from March 2020 to May 2020. A total of 14 patients (22.5%) presented with obvious typical symptoms of coronavirus disease 2019 associated viremia and were identified after they developed symptoms during admission or after the implementation of universal testing for all obstetric admissions. A total of 62 mothers were screened positive for the SARS-CoV-2 infection. Length of stay was higher in the symptomatic group. The median length of stay was 4 days for the asymptomatic cases while it was 6 days for the symptomatic cases. Amniotic fluid was meconium stained in (12.5%) of the asymptomatic group and in 30.8% in the symptomatic group. Post discharge mothers with asymptomatic SARS-CoV-2 infection were more likely to breastfeed their infants. OR (95% CI) was 1.4 (1.02–1.90) and P-value was 0.0327. There was non-statistically significant absence of perinatal morbidities or mortalities among symptomatic and asymptomatic mothers.
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