Special Issue Title: Inflammation during embryonic development - Studying the consequences of chorioamnionitis
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· Deadline for manuscript submissions: 1 October 2020
Guest Editor
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Prof. Nikolaos Papadopoulos
University Hospital of Alexandroupolis, Medical School,
Democritus University of Thrace, Dragana, Alexandroupolis, 68132, Evros Greece
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Website | E-Mail
Interests: Fetal development; chorioamnionitis; consequences
Special Issue Information
Dear Colleagues,
Inflammation during embryonic development from highly virulent organisms constitutes a serious complication of pregnancy with a high rate of fetal morbidity and mortality. This condition is due mostly from microoranisms such as, E. coli, group B streptococci and anaerobic bacteria that are normally present in the vagina. These pathogenic microorganisms ascend into the uterine cavity affecting at first the membranes that surround the fetus (chorion and amnion), a condition called acute chorioamnionitis. Clinically, the chorioamnionitis is characterized by maternal fever, leukocytosis, tachycardia, uterine tenderness and finally causing an inflammatory cascade that leads to preterm rupture of membranes / preterm birth.
Evidence from humans and experimental models has been shown that chorioamnionitis is associated with a fetal inflammatory response which is characterized by increased release of systemic inflammatory cytokine and toxic molecules. It seems that these substances induce secondary growth disorders on fetal development which have been associated with the occurrence of serious complications and congenital malformations in various organs of the fetus. Disturbances that have been recorded in the development of the brain, sensory organs of sight and hearing, in the respiratory, gastrointestinal and urinary tract, and finally disorders of embryonic hematopoiesis in the liver, spleen and thymus gland.
Prof. Papadopoulos Nikolas
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at https://ceog.imrpress.org by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Clinical and Experimental Obstetrics & Gynecology is an international peer-reviewed open access quarterly journal published by IMR Press.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is $1250. We normally offer a discount about 30% (APC: $850) to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.
Keywords
Fetal development; chorioamnionitis; consequences
