Special Issues

Special Issue Title: Updates in obstetrics and gynecology

· Print Special Issue Flyer

· Deadline for manuscript submissions: 30 September 2021

Special Issue Editor

Guest Editor

 Antonio Simone Laganà, MD, PhD

Department of Obstetrics and Gynecology, “Filippo Del Ponte” Hospital, University of Insubria, Varese, Italy 

Website | E-Mail

Interests: Minimally invasive gynecology; Laparoscopy; Hysteroscopy; Female infertility; Endometriosis; Reproductive immunology; Gynecological endocrinology

  Simone Garzon, MD

 Department of Obstetrics and Gynecology, “Filippo Del Ponte” Hospital, University of Insubria, Varese, Italy

Website | E-Mail

Interests: Gynecology oncology; Endometrial cancer; Minimally invasive gynecology; Robotic surgery; Laparoscopy; Hysteroscopy; Female infertility; Endometriosis; Assisted reproduction; Gynecological endocrinology

Special Issue Information

Dear Colleagues,

The ideas of this special issue titled "updates in obstetrics and gynecology" derives from the desire to create a collection of manuscripts providing new evidence or summarizing the most recent available pieces of evidence in the field of women's care. From new advances in the treatment of gynecological malignancies to the study of molecular mechanisms involved in pathologies affecting fertility, from the investigation of fetal abnormalities by ultrasound to the most recent advances in obstetric care in the setting of delivery room, this special issue is aimed to provide a collection able to became the starting point of new researches.

M.D., Ph.D. Antonio Simone Laganà and M.D. Simone Garzon

Guest Editors


Manuscript Submission Information

Manuscripts should be submitted online at https://ceog.imrpress.org by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Clinical and Experimental Obstetrics & Gynecology is an international peer-reviewed open access quarterly journal published by IMR Press.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is $1250. Submitted papers should be well formatted and use good English.


Gynecological malignancies; Fertility; Fetal abnormalities; Obstetric care

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Accepted Papers

1. CEOG2240
Iulia Baciu, Dalila-Ana Domuncu, Tiberiu Domuncu, Anca Marina Ciobanu, Theodor Voiosu, Gheorghe Peltecu, Anca Maria Panaitescu. Tenofovir disoproxil fumarate for preventing mother-to-child transmission of hepatitis B: a literature review. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 9-18.

2. CEOG2242
Hong Zhang, Wen-Li Liu, Jia-Lin Liu, Ming-Cheng Li. Identification and characteristics of antimicrobial-resistant Group B Streptococcus isolated from maternal birth canals at a university-affiliated hospital, China. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 253-256.  

3. CEOG2244
Mehmet Sait Bakır , Özer Birge, Ceyda Karadag, Can Dinc, Ahmet Boduroglu, Tayup Simsek.Ligneous cervico-vaginitis mimicking female genital tract malignancies.linical and Experimental Obstetrics & Gynecology

4. CEOG2248
Qian Hu, Mohammed Sharooq Paramboor, Tao Guo. Diagnosis and management of intramural ectopic pregnancy.Clinical and Experimental Obstetrics & Gynecology

5. CEOG2249
Rui-Ke Liu, Li Li, Xue-Qian Du, Ying Wang, Shuai Chen, Gui-Lian Li, Gui-Fang Li. Gestational age affects the cerebellum development in neonatal infants: establishment of cerebellar extrauterine reference values as a function of gestational age. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 395-401.

6. CEOG2526
Sema Karakaş, Cihan Kaya, Sebastian, Daniel Schäfer, Mislav Mikuš, Milan Terzic, Bekhzod Abdullaev, Alessandra Andrisani. Fertility-sparing in cancer patients. Clinical and Experimental Obstetrics & Gynecology. 

7. CEOG2527
Vesna Elvedi-Gašparović, Mislav Mikuš, Petrana Beljan, Adam Vrbanić, Giulio Bonaldo*, Giovanni Buzzaccarini, Marco Noventa, Maurizio Nicola D'Alterio, Snježana Škrablin. The impact of maternal eating disorders and pre-pregnancy body mass index on pregnancy outcome: a brief. Clinical and Experimental Obstetrics & Gynecology.

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Fertility-sparing in cancer patients
Sema Karakaş, Cihan Kaya, Sebastian Daniel Schäfer, Mislav Mikuš, Milan Terzic, Bekhzod Abdullaev, Alessandra Andrisani
Clinical and Experimental Obstetrics & Gynecology    2021, 48 (4): 787-794.   DOI: 10.31083/j.ceog4804126
Abstract116)   HTML11)    PDF(pc) (138KB)(83)       Save

Objective: This review aimed to investigate and summarize the current evidence on fertility-sparing options in cancer patients. Mechanism: Fertility preservation methods are becoming popular through the improved prognosis of cancer patients at a younger age and early diagnostic tools. However, currently, more and more women are suffering from iatrogenic ovarian failure and fertility loss because of cancer treatment. Most treatments have been used for hematological malignancies, but different gynecological cancers can be eligible. Findings in brief: Fertility preserving strategies such as oocyte and embryo cryopreservation, ovarian tissue preservation, ovarian transposition, and aspiration of ovarian follicles are the methods that could be suggested to the patients. The current knowledge supports oocyte and embryo cryopreservation as feasible, safe, and effective treatment approaches for cancer patients seeking fertility preservation. Conclusions: Robust evidence is still needed to prove the effectiveness of cryopreservation of the ovarian tissue and ovarian follicle aspiration approaches since these techniques are still in early their steps.
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Validation of Pipelle endometrial biopsy in patients with abnormal uterine bleeding in Kazakhstani healthcare setting
Gulzhanat Aimagambetova, Aiym Kaiyrlykyzy, Gauri Bapayeva, Talshyn Ukybassova, Kamila Kenbayeva, Bakytkali Ibrayimov, Alla Lyasova, Giulio Bonaldo, Giovanni Buzzaccarini, Marco Noventa, Antonio Simone Laganà, Milan Terzic
Clinical and Experimental Obstetrics & Gynecology    2021, 48 (3): 670-675.   DOI: 10.31083/j.ceog.2021.03.2510
Abstract122)   HTML9)    PDF(pc) (120KB)(117)       Save

Background: Abnormal uterine bleeding is a common sign which cover various conditions e/o pathologies. Different approaches are used to evaluate this condition. The aim of this study was to investigate the validity of Pipelle biopsy for endometrial sampling in Kazakhstani women with abnormal uterine bleeding. For this reason, we carried out a prospective study of 120 patients who underwent endometrial sampling due to abnormal uterine bleeding in a tertiary hospital setting in Kazakhstan. Methods: Statistics included descriptive analysis to evaluate the frequency of various endometrial conditions. The validity of Pipelle biopsy sampling was calculated by estimating sensitivity, specificity, accuracy, and positive and negative predictive values. For the Pipelle sampling validity assessment, we analyzed 120 samples, as 21 patients with insufficient samples were excluded. Results: Overall, concordance in histopathologic results was 92.93%. Pipelle sampling identified two cases of adenocarcinoma in our group. Moreover, endometrial hyperplasia was detected with 71.43% sensitivity, 98.82% specificity, PPV of 90.91% and NPV of 95.45%. However, the Pipelle reliability was low in cases of endometrial polyps. In conclusion, the Pipelle method was found to be valid for the diagnosis of endometrial hyperplasia and adenocarcinoma with high SN, SP, PPV and NPV. Conclusions: The Pipelle technique for evaluation of abnormal uterine bleeding in the Kazakhstani health care setting is a useful method with the highest efficacy in ruling out endometrial hyperplasia and diagnosing adenocarcinoma. If endometrial polyp was suspected under ultrasound scan in patients with abnormal uterine bleeding, physicians should consider other tools for endometrial sampling.
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Effectiveness of platelet-rich plasma treatment in perineal trauma: a case report
Ayşe Gül Kabakcı, Memduha Gülhal Bozkır
Clinical and Experimental Obstetrics & Gynecology    2021, 48 (3): 728-732.   DOI: 10.31083/j.ceog.2021.03.2464
Abstract85)   HTML7)    PDF(pc) (544KB)(122)       Save

Background: Approximately 85% of women will experience perineal trauma during vaginal birth. Pain is one of the most important long-term complications of perineal trauma. The quality of life is negatively affected, the pain experienced is a cause of negative prejudice against future vaginal birth. Platelet rich plasma treatment is a new approach to treating the pain and healing perineal trauma. Case presentation: A 31-year-old female patient presented to the Gynaecology department with pain during urination, defecation, in coitus, during menstruation, while walking and while sitting. The pain continued to increase 10 years after the first birth and analgesic medications were ineffective. After gynacological examination, a diagnosis was made of perineal trauma (second degree) due to deep episiotomy in the first vaginal birth. The patient received three platelet rich plasma treatments at three-week intervals. Repeated assessments showed noticeable reduction in pain and improvements in scar healing. Conclusions: Perineal trauma was treated with platelet rich plasma containing high platelet concentrations and various growth factors. The patient's intense pain complaints ended.
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