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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (3): 590-593    DOI: 10.31083/j.ceog.2021.03.2434
Original Research Previous articles | Next articles
The effect of laparoscopic ovarian drilling on timing of menopause in patients with polycystic ovary syndrome: 29 years of follow-up data
Gonca Özten Dere1, Esra Uyanik1, Fatih Aktoz1, Pınar Çalış1, Sezcan Mümüşoğlu1, Hakan Yarali1, Gürkan Bozdağ1, *()
1Department of Obstetrics and Gynecology, Hacettepe University School of Medicine, 06080 Ankara, Turkey
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Abstract  
Background: Despite significantly improved rates of ovulation and pregnancy after laparoscopic ovarian drilling (LOD) in patients with polycystic ovary syndrome (PCOS), one should remain cautious of this procedure due to the associated risk of post-operative adhesions and a significant decrease in ovarian reserve markers. In this longitudinal follow-up study, we aimed to evaluate the long-term effects of LOD on the timing of menopause. Methods: A total of 83 patients were identified who had undergone LOD between December 1991 and December 1996. Of the 13 patients that we were able to reach, two had undergone unilateral LOD and were excluded, leaving 11 patients to be analysed. Results: The median age at the time of LOD was 25 (range 19–35) years. The median age at the time of the current analysis was 52 (range 46–64) years. Whereas two of these patients had surgical menopause at the age of 35 and 47 due to leiomyoma, four patients had natural menopause between the ages of 45 to 52 years. Although five patients were still having regular cycles at the age of 46 to 54 years at the time of the study, we do not have any biochemical data to evaluate their ovulatory status. With respect to fecundity, whereas nine out of 11 patients conceived spontaneously, two required assisted reproduction treatment. Discussion: According to the findings from a limited number of patients, LOD does not appear to have any negative effect on the timing of menopause.
Key words:  Laparoscopic ovarian drilling      Polycystic ovary syndrome      Menopause     
Submitted:  24 December 2020      Revised:  22 March 2021      Accepted:  29 March 2021      Published:  15 June 2021     
*Corresponding Author(s):  Gürkan Bozdağ     E-mail:  gbozdag75@yahoo.com

Cite this article: 

Gonca Özten Dere, Esra Uyanik, Fatih Aktoz, Pınar Çalış, Sezcan Mümüşoğlu, Hakan Yarali, Gürkan Bozdağ. The effect of laparoscopic ovarian drilling on timing of menopause in patients with polycystic ovary syndrome: 29 years of follow-up data. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 590-593.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.03.2434     OR     https://ceog.imrpress.com/EN/Y2021/V48/I3/590

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