Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (2): 439-443    DOI: 10.31083/j.ceog.2021.02.2194
Case Report Previous articles | Next articles
Prenatal sonographic findings and management of placental mesenchymal dysplasia
Suchaya Luewan1, Pakorn Chaksuwat1, Tip Pongsuvareeyakul2, Theera Tongsong1, *()
1Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, Thailand
2Department of Pathology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, Thailand
Download:  PDF(1894KB)  ( 109 ) Full text   ( 12 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Placental mesenchymal dysplasia (PMD) is a rare disorder of the placenta characterized by placentomegaly with diffuse hydropic stem villous, aneurysmally dilated vessels, and lack of trophoblastic proliferation. Case: The prenatal ultrasound of a 34-year-old woman (G1P0) at 33 weeks of gestation showed an enlarged placenta with multiple cystic lesions, heterogeneous echoes with no active blood flow, and fetal growth restriction (FGR). The differential diagnosis involved partial mole, placental hemorrhage, and PMD. She developed preeclampsia at 38 weeks of gestation and gave birth to a normally formed, growth-restricted baby. The placenta, weighing 785 g, showed scattered cystic vesicles in the parenchyma. The histology shows enlarged edematous stem villi with occasional cistern formation and no area of chorioangioma or features of molar pregnancy. PMD associated fetal growth restriction was diagnosed. Conclusion: PMD has prenatal ultrasound result resembling those of partial mole, placental hemorrhage and chorioangioma, but the fetus is phenotypically normal. Nevertheless, fetal surveillance is essential.
Key words:  Placental mesenchymal dysplasia      Prenatal diagnosis      Ultrasound     
Submitted:  20 June 2020      Revised:  22 August 2020      Accepted:  31 August 2020      Published:  15 April 2021     
Fund: 
CMU-2563/Chiang Mai University Research Fund
*Corresponding Author(s):  Theera Tongsong     E-mail:  theera.t@cmu.ac.th

Cite this article: 

Suchaya Luewan, Pakorn Chaksuwat, Tip Pongsuvareeyakul, Theera Tongsong. Prenatal sonographic findings and management of placental mesenchymal dysplasia. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 439-443.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.02.2194     OR     https://ceog.imrpress.com/EN/Y2021/V48/I2/439

[1] Christina M. Moisidis-Tesch, Nicole Vedder, Norman A. Ginsberg. Rapid rate of growth in adnexal masses, despite benign appearance on ultrasound, was associated with malignancy. A retrospective analysis of 48 consecutive cases from a single institution[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1081-1088.
[2] Ryuichi Shimaoka, Tomomi Shiga, Ken-ichirou Morishige. Effect of ritodrine tocolysis on fetal cardiac output distribution to the placenta[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1126-1131.
[3] Mahmoud Alalfy, Soha Talaat Hamed, Alaa Sobhi Abd El Ghani, Ahmed Elgazzar, Amr Abbassy, Ahmed S. S. A. Rashwan, Omar Nagy, Mohamed A Shalaby, Hatem Hassan, Asmaa Ibrahem, Hesham Kamal, Reham Mahrous, Eman Kamal. The accuracy of 3D-TUI and 3D power Doppler using Alalfy simple criteria in the diagnosis of placenta accreta spectrum[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1132-1140.
[4] Ji-Chen Wang, De-Ying Wei, Chen Su, Qi Han, Yong-Hao Gai. Intraoperative management of a Robert's uterus without hematometra in blind hemi-cavity preoperatively misdiagnosed as septate uterus[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1219-1223.
[5] Thanakorn Heetchuay, Thotsapon Trakulmungkichkarn, Noel Pabalan, Nutthaphon Imsom-Somboon. Reference values of fetal atrioventricular time intervals derive from antegrade late diastolic arterial blood flow (ALDAF) from 14 to 40 weeks of gestation[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(4): 867-874.
[6] Maria Aparecida Mazzutti Verlangieri Carmo, Helmer Herren, Francisco J. C. Dos-Reis, Fabricio Da Silva Costa, Julio C. Rosa-e-Silva, Antonio Alberto Nogueira, Omero Benedicto Poli-Neto. Reliability and agreement of three-dimensional/four-dimensional transperineal ultrasound in women with chronic pelvic pain[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 494-499.
[7] Lejla Kamerić, Anis Cerovac, Mirzeta Rizvanović, Alen Kamerić, Mahira Jahić, Dubravko Habek. Frequency of cesarean section in pregnant women with risk factors for preeclampsia: prospective cohort study[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 561-566.
[8] Özgür Koçak, Cem Koçak. Finding the best formulas to estimate fetal weight based on ultrasound for the Turkish population: a comparison of 24 formulas[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 676-685.
[9] Angel Yordanov, Krasimira Zhelyaskova. Prenatal ultrasonographic diagnosis of fetal scrotal inguinal hernia: a case report and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 723-727.
[10] Ryuichi Shimaoka, Tomomi Shiga, Ken-ichirou Morishige. Change in uterine artery blood flow with intrauterine balloon tamponade[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 307-311.
[11] Jun Wang, Xiao-Dong Zhao, Gang Wang, Wei-Ming Li, Hua Guo, Jia-Mei Gou, Guo-Juan Feng, Jing Rao. The accuracy of pulmonary ultrasound in the diagnosis and monitoring of community-acquired pneumonia in women of childbearing age[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 381-388.
[12] Rui-Ke Liu, Li Li, Xue-Qian Du, Ying Wang, Shuai Chen, Gui-Lian Li, Gui-Fang Li. Gestational age affects the cerebellum development in neonatal infants: establishment of cerebellar extrauterine reference values as a function of gestational age[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 395-401.
[13] Saša Raičević, Duško Kljakić, Filip Vukmirović, Miloš Z. Milosavljević. A giant placental chorioangioma with a resultant live birth; a discussion of management options[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 426-430.
[14] Duygu Adıyaman, Bahar Konuralp Atakul, Melda Kuyucu, Hakan Gölbasi, Atalay Ekin. Difference between near-field and far-field of middle cerebral artery doppler pulsatility index and peak systolic velocity: a prospective study[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 66-72.
[15] Sureyya Saridas Demir, Erkan Cağliyan, Sabahattin Altunyurt. Retrospective analysis of pregnancy terminations and indications in a tertiary center[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 85-90.
No Suggested Reading articles found!