Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (2): 323-330    DOI: 10.31083/j.ceog.2021.02.2329
Original Research Previous articles | Next articles
Clinical factors associated with anxiety and depression in Korean women with abnormal uterine bleeding
Hae Nam Lee1, Hui Ryeon Ju1, Ji Min Seo1, Gi Soo Um1, Min Jeong Kim1, *()
1Department of Obstetrics and Gynecology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 14647 Seoul, Republic of Korea
Download:  PDF(2659KB)  ( 111 ) Full text   ( 7 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
The aims of the study were to investigate the prevalence of anxiety and depression and to correlate symptoms of anxiety and depression with abnormal uterine bleeding (AUB) in Korean women. Our study included 124 Korean premenopausal women aged 15–55 without treatment of psychiatric disorders, who visited one university hospital due to AUB between September 2015 and December 2019. The Korean Beck Anxiety Inventory (K-BAI) and the Korean Beck Depression-II (K-BDI-II) were used to assess Anxiety and depression symptoms. We also analyzed obstetrical and clinical data to assess the association between anxiety and depression with AUB. The cut-off scores for possible anxiety disorder were met by 37.9% (47 women) of the patients and for possible depression disorder by 19.5% (24 women). The most common menstrual associated symptoms were heavy menstrual bleeding (80.6%), dysmenorrhea (55.6%), and irregular menstrual cycles (33.9%). More women with AUB in our study had anxiety as measured by the K-BAI and depression as measured by the K-BDI-II than general Korean population. A history of abortion and cesarean section (C/sec) were related with anxiety, whereas a history of minor surgery was related to depression. Anxiety and depression (r = 0.629, P < 0.001) were correlated with AUB. According to age, variable factors affect anxiety (history of abortion, history of C/sec, minor surgery, Body mass index [BMI], history of OCs) and depression (BMI ≥ 25, history of minor surgery). We have found that anxiety and depression seem to be underestimated in Korean women with AUB symptoms. The relationship between the development of anxiety and depression with variable factors are unknown and therefore, further study is needed to clarify and understand the effects of AUB. To improve the health of women with AUB, screening for mental health issues is needed for early detection and treatment of anxiety and depression.
Key words:  Abnormal uterine bleeding      Heavy menstrual bleeding      Anxiety      Depression     
Submitted:  18 October 2020      Revised:  04 January 2021      Accepted:  25 January 2021      Published:  15 April 2021     
Fund: 
Institute of Clinical Medicine Research of Bucheon St. Mary's Hospital, Research Fund, 2020
HC14C1062/Korea Health Technology R&D Project through the Korean Health Industry Development Institute (KHIDI)
*Corresponding Author(s):  Min Jeong Kim     E-mail:  poouh74@catholic.ac.kr

Cite this article: 

Hae Nam Lee, Hui Ryeon Ju, Ji Min Seo, Gi Soo Um, Min Jeong Kim. Clinical factors associated with anxiety and depression in Korean women with abnormal uterine bleeding. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 323-330.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.02.2329     OR     https://ceog.imrpress.com/EN/Y2021/V48/I2/323

[1] Gyung-Mee Kim, Jung Ahn Lee, Sung Woo Park, Jung Goo Lee, Gyun-Ho Jeon. Are plasma Brain-Derived Neurotrophic Factor or reproductive hormones related to depression in PCOS patients?: a prospective cohort study[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1146-1153.
[2] Anjeza Xholli, Anna Biasioli, Giovanni Grandi, Angelo Cagnacci. Dienogest-based hormonal contraception induced changes in the ultrasound presentation of the uterus and menstrual pain[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1186-1192.
[3] Rocio Montejo, Jonas Hermansson, Lena Sandin Wranker, Louise Danielsson. Doula support in office hysteroscopy: results from a pilot study[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(4): 955-961.
[4] Banuhan Şahin, Buğra Şahin, Pervin Karlı, Görker Sel, Şafak Hatırnaz, Osman Fadıl Kara, Andrea Tinelli. Level of depression and hopelessness among women with infertility during the outbreak of COVID-19: a cross-sectional investigation[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 594-600.
[5] Gulzhanat Aimagambetova, Aiym Kaiyrlykyzy, Gauri Bapayeva, Talshyn Ukybassova, Kamila Kenbayeva, Bakytkali Ibrayimov, Alla Lyasova, Giulio Bonaldo, Giovanni Buzzaccarini, Marco Noventa, Antonio Simone Laganà, Milan Terzic. Validation of Pipelle endometrial biopsy in patients with abnormal uterine bleeding in Kazakhstani healthcare setting[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 670-675.
[6] Hazem Al-Mandeel. Should diagnostic hysteroscopy be performed routinely following thermal balloon endometrial ablation? A case report of thermal bowel injury and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 423-425.
[7] L.L. Xu, J.Q. Li, Y.Q. Pu, C. Zhou, S.W. Feng, Q. Luo. Effect of prenatal depression during late pregnancy on maternal and neonatal outcomes[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 681-686.
[8] Y. Akdemir, M. Karadeniz. A psychological factor associated with pain during intrauterine device insertion: emotional reactivity[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 335-340.
[9] G. Keren, G. Ayala. Factors associated with hyperemesis gravidarum[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 391-395.
[10] J.D. Jaremek, D.R. Chinniah, A. Słopień, P. Rynio, R. Słopień. Menopausal depression - state of art[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 859-861.
[11] H. Aydoğmuş, S. Gençdal, Z. Kolsuz, F. Elmalı, S. Aydoğmuş, S. Kelekçi. Is there a relationship between systemic inflammatory markers and abnormal uterine bleeding in unclassifiable cases according to the PALM-COEIN system?[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 752-756.
[12] A. Średniawa, K. Kruk, D. Ł. Jarczewska, K. Żabicka, M. Golonka, R. Krępa, T. Tomasik. Postpartum depression and breastfeeding in primary care in Krakow, Poland[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 880-885.
[13] K. Bakay, H. Ulubaşoğlu, T. Atan, H. Alaçam, D. Güven, S. Batioğlu. The effect of physical activity on the levels of the hormones, serotonin and melatonin in premenstrual syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(3): 425-427.
[14] E. Djakovic, S. Rakic. Depression, anxiety, and stress after preterm delivery: role of previous progesterone therapy[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(2): 214-217.
[15] A.M. Eman, M.E. Mahmoud. Effect of aerobic exercises versus foot reflexology on post-menopausal depression[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(5): 726-729.
No Suggested Reading articles found!