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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (2): 253-256    DOI: 10.31083/j.ceog.2021.02.2242
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Identification and characteristics of antimicrobial-resistant Group B Streptococcus isolated from maternal birth canals at a university-affiliated hospital, China
Hong Zhang1, Wen-Li Liu2, Jia-Lin Liu2, Ming-Cheng Li2, *()
1Department of Reproductive Medicine, Associated Hospital, Beihua University, 132000 Jilin, Jilin, China
2Department of Clinical Diagnosis, School of Laboratory Medicine, Beihua University, 132013 Jilin, Jilin, China
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Abstract  
Purpose of investigation: This study aimed to ascertain the colonization rate of Group B Streptococcus (GBS) in the birth canals of late-pregnant women, and to demonstrate the characteristics of the origins of antibiotic-resistance. Materials and Methods: A prospective survey of pregnant women from 2017 to 2019 at a university-affiliated hospital in China was conducted. A total of 275 pregnant women with a pregnancy between 35 and 37 weeks were included in the study. Vaginal secretions and rectal swabs were tested by GBS separation to identify cultures, and an agar doubling dilution method was performed to assess drug sensitivity. Results: In 275 pregnant women, 20 cases were GBS screen-positive for the vaginal swabs with a GBS colonization rate of 7.27%. In addition, 16 isolates from the rectal swabs were also GBS screen-positive. Of 20 isolates from the vaginal swabs, 90.0% were resistant to tetracycline, 70.0% were resistant to erythromycin, 40.0% were resistant to clindamycin, 40.0% were resistant to levofloxacin and 30.0% resistant to chloromycetin. All isolates were susceptible to penicillin G, vancomycin, and linezolid. Conclusions: The higher prevalence of GBS colonization among pregnant women indicated the critical need for screening GBS colonization in late-pregnant women in the region. The study revealed the resistant patterns of GBS colonization and inferred a possible mechanism of the GBS resistance to antimicrobial agents used as animal growth promotion substances.
Key words:  Group B Streptococcus      Pregnant woman      Colonization      Resistance     
Submitted:  28 July 2020      Revised:  07 September 2020      Accepted:  23 September 2020      Published:  15 April 2021     
Fund: 
20190905006SF/Jilin Science and Technology Development Program
2019C052-7/Jilin Development and Reform Commission
2012-133/Jilin Education Department Program
*Corresponding Author(s):  limingcheng1964@163.com; limingcheng@beihua.edu.cn (Ming-Cheng Li)   

Cite this article: 

Hong Zhang, Wen-Li Liu, Jia-Lin Liu, Ming-Cheng Li. Identification and characteristics of antimicrobial-resistant Group B Streptococcus isolated from maternal birth canals at a university-affiliated hospital, China. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 253-256.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.02.2242     OR     https://ceog.imrpress.com/EN/Y2021/V48/I2/253

[1] Zhu Chen, Hui Huang, Jingcen Hu, Shuyu Wang, Liang Xia. Circulating neutrophil gelatinase-associated lipocalin and gestational diabetes mellitus: a meta-analysis[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1206-1214.
[2] Wassan Nori, Muna Abdulghani, Ali B Roomi, Wisam Akram. To operate or to wait? Doppler indices as predictors for medical termination for first trimester missed abortion[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 168-174.
[3] H.M.G. Youssef, E.S. Marei, L.A. Rashed. Long non-coding RNA steroid receptor activator in polycystic ovary syndrome: possible association with metabolic syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 757-762.
[4] H. Bagci, R. Melekoglu, M.F. Gursu, A. Akyol, F. G. Bulmus. Associations between serum levels of adiponectin and resistin and metabolic parameters in pregnant women with gestational diabetes mellitus[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 539-543.
[5] M.Y. Oncel, S. Celen, G. Demirel, F.E. Canpolat, E. Calisici, R. Ozdemir, S.S. Oguz, S. Saygan, N. Danisman, U. Dilmen. Effect of maternal cervical bacterial colonization on neonatal outcome in high-risk pregnancies: results from a tertiary maternity center in Turkey[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(4): 485-489.
[6] X.F. Lin, R.R. Wu, J. Du, Y.C. Liao, Y. Du, Y. Ye, Y. Wang, X.B. Zhang, C. Wu, A. Chen. Exploring the significance of sex hormone-binding globulin examination in the treament of women with polycystic ovarian syndrome (PCOS)[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(3): 315-320.
[7] M. Nishimoto, Y. Miyahara, Y. Ebina, M. Deguchi, S. Matsuoka, H. Yamada. Viper bite during pregnancy: case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(2): 243-245.
[8] L. Hu, H. Shen, Q.F. Wu, L. Tian, M.H. Hu. Treatment of polycystic ovarian syndrome with insulin resistance by insulin-sensitizer[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(3): 288-292.
[9] B. Yildirim, O. Celik, S. Aydin. Adropin: a key component and potential gatekeeper of metabolic disturbances in policystic ovarian syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2014, 41(3): 310-312.
[10] H. Itoh, Y. Kawano, Y. Furukawa, H. Matsumoto, A. Yuge, H. Narahara. The role of serum adiponectin levels in women with polycystic ovarian syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2013, 40(4): 531-535.
[11] A.N. Unluer, R.B. Findik, N. Sevinc, J. Karakaya. Comparison of HbA1c levels in obese and non-obese polycystic ovarian patients[J]. Clinical and Experimental Obstetrics & Gynecology, 2013, 40(1): 148-150.
[12] G. Paradisi, M. Bracaglia, F. Basile, S. D’Ippolito, F. Di Nicuolo, F. Ianniello, L. Quagliozzi, L. Donati, A. Labianca, C. Di Cesare, M. Viggiano, A. Biaggi, C. De Waure, F. Andreotti, N. Di Simone, A. Caruso. Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women[J]. Clinical and Experimental Obstetrics & Gynecology, 2012, 39(2): 153-159.
[13] H. Elshoreya, F. Steinberg, R. Perry, C. Hansen, B. Milcareck, S. Elkouachi, J.H. Check. Serum adiponectin levels are significantly reduced during the second half of normal pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2011, 38(3): 211-213.
[14] R. Orvieto, V. Shuhat, G. Liberty, R. Homburg, E.Y. Anteby, R. Nahum,J. Rabinson, S. Meltcer. Serum retinol-binding protein-4 levels in polycystic ovary syndrome patients undergoing controlled ovarian hyperstimulation for in-vitro fertilization cycle[J]. Clinical and Experimental Obstetrics & Gynecology, 2010, 37(2): 100-104.
[15] L. Y. Zhang, X. C. Zhang, L. D. Wang, Z. F. Zhang, P. L. Li. Increased expression of GRP94 protein is associated with decreased sensitivity to adriamycin in ovarian carcinoma cell lines[J]. Clinical and Experimental Obstetrics & Gynecology, 2008, 35(4): 264-266.
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