Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (2): 265-269    DOI: 10.12891/ceog4624.2019
Original Research Previous articles | Next articles
Advanced maternal age and neonatal outcomes in Malta
M. Collict1, *(), Y. Mucat Baron1, M. Gatt2, N. Calleja2
1Department of Obsterics and Gynaecology, Mater Dei Hospital, Msida
2Department of Health, Information and Research, Pieta, Malta
Download:  PDF(939KB)  ( 44 ) Full text   ( 6 )
Export:  BibTeX | EndNote (RIS)      
Abstract  

Introduction: During the past three decades, significant increases in childbirth at advanced maternal age (AMA) have been noted in different high-income countries. Objective: The aim of this study is to assess for the association between AMA and different neonatal outcomes in Malta. Multivariate regression analysis was carried out. Materials and Methods: Data was derived from the National Obstetric Information System. All mothers of 20 years and older, who delivered singleton babies in Malta and Gozo between 1st January 2000 and 31st December 2014 were studied.Results: The study population included 55, 943 singleton births. Our results clearly show that the percentage of preterm babies increased and the birth weight decreased with advancing maternal age. The adjusted rates of stillbirths and rates of infants that died in less than 28 days also increased with age. A significant increase in chromosomal abnormalities was also detected in mothers over 40 years.Conclusion: This study demonstrates that AMA in Malta significantly increases the risk for preterm births, low birth weight, still births and neonatal deaths. The set-up of a multidisciplinary specialized clinic may prove useful in improving outcome in pregnancies of women with AMA.

Key words:  Preterm births      Advanced maternal age (AMA)      Neonatal outcome      Malta     
Published:  10 April 2019     
*Corresponding Author(s):  M. COLLICT     E-mail:  mandy.caruana@gov.mt

Cite this article: 

M. Collict, Y. Mucat Baron, M. Gatt, N. Calleja. Advanced maternal age and neonatal outcomes in Malta. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 265-269.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog4624.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I2/265

[1] Ugo Indraccolo, Maria Giulia Lombana Marino, Beatrice Bianchi, Silvia Catagini, Danila Morano, Pantaleo Greco. Symphysis-fundal height correlates with adverse delivery and neonatal outcomes in induced full-term and premature pregnancies[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 637-641.
[2] I. Babović, M. Matić, S. Plešinac. Woman with Marfan syndrome in pregnancy: good maternal and fetal outcome – a case report and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 920-923.
[3] K.P. Fuller, S. DeGroff, A.F. Borgida. Neonatal outcomes based on antenatal corticosteroid exposure time for infants delivered between 23 and 34 weeks gestation[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 247-251.
[4] Y. Cakiroglu, E. Doger, S. Yildirim Kopuk, A. Gunlemez, D. Oguz, E. Caliskan. Does amnioreduction increase success of emergency cervical cerclage in cases with advanced cervical dilatation and protruding membranes?[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(5): 708-712.
[5] N. Aka, Ş. Arpacı, F. Vura, G. Köse. Perinatal and neonatal outcomes of maternal heart diseases[J]. Clinical and Experimental Obstetrics & Gynecology, 2016, 43(4): 560-564.
[6] M. Soilemetzidis, P. Pinidis, N. Tsagias, A. Ammari, A. Liberis, V. Liberis, G. Galazios, P. Tsikouras. The effectiveness of misoprostol or dinoprostone in neonatal outcome after labour induction in post-term nulliparas[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(5): 649-652.
[7] M.Y. Oncel, S. Celen, G. Demirel, F.E. Canpolat, E. Calisici, R. Ozdemir, S.S. Oguz, S. Saygan, N. Danisman, U. Dilmen. Effect of maternal cervical bacterial colonization on neonatal outcome in high-risk pregnancies: results from a tertiary maternity center in Turkey[J]. Clinical and Experimental Obstetrics & Gynecology, 2015, 42(4): 485-489.
[8] G. Pados, M. Zafrakas, D. Tsolakidis, E. Assimakopoulos, H. Bili, B.C. Tarlatzis. Obstetric and neonatal outcome after assisted fertilization and spontaneous conception: a comparative study[J]. Clinical and Experimental Obstetrics & Gynecology, 2012, 39(4): 448-451.
[9] I. Babovic, S. Plesinac. Doppler examination in the evaluation of outcomes in pregnancies complicated by gestational hypertension and fetal intrauterine growth retardation - is it enough?[J]. Clinical and Experimental Obstetrics & Gynecology, 2012, 39(2): 222-224.
[10] D. Eroglu, M. Oktem, F. Yanik, E. Kuscu. Labor induction at term: a comparison of the effects of 50 μg and 25 μg vaginal misoprostol[J]. Clinical and Experimental Obstetrics & Gynecology, 2007, 34(2): 102-105.
[11] R. Axt, M. Hippach, D. Mink, H. J. Hendrik, A. K. Ertan, W. Schmidt. Maternal and neonatal outcome in a monochorionic twin pregnancy complicated by single intrauterine demise[J]. Clinical and Experimental Obstetrics & Gynecology, 1999, 26(3-4): 155-157.
[12] F. Diani, S. Venanzi, G. Zanconato, S. Murari, C. Moscatelli, A. Torinetto. Fetal macrosomia and management of delivery[J]. Clinical and Experimental Obstetrics & Gynecology, 1997, 24(4): 212-214.
[13] A. Restaino, C. Campobasso A. D’Aloya, A. D. Abbruzzese, A. Valerio F. Pansini. Cirrhosis and pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 1996, 23(4): 236-239.
[14] M. BRESADOLA, F. LO MASTRO, V. ARENA, L. BELLAVEGLIA, F. SCARPELLINI. Preterm labour and neonatal parameters[J]. Clinical and Experimental Obstetrics & Gynecology, 1995, 22(3): 235-239.
No Suggested Reading articles found!