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Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (2): 288-291    DOI: 10.12891/ceog3385.2017
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Virtopsy in conjoined ischiopagus twins
M.P. Biso1, P. Sala1, *(), V.G. Vellone2, G. Minetti3, C.R. Gaggero1, M. Foppiano1, E. Fulcheri4, P. De Biasio1
1 Unit of Obstetrics and Gynecology, IRCCS A.O.U. San Martino IST, Genoa, Italy
2 Department of Pathology, University of Genoa and IRCCS A.O.U. San Martino IST, Genoa, Italy
3 Department of Radiology, IRCCS A.O.U. San Martino IST, Genoa, Italy
4 Department of Pathology, University of Genoa and IRCCS G. Gaslini Institute, Genoa, Italy
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Abstract  
Purpose of investigation: To propose a multidisciplinary protocol for postmortem disclosure of complex fetal malformations, comparing ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and autopsy in a case of conjoined ischiopagus twins. Materials and Methods: A screening second-trimester ultrasound diagnosed ischiopagus twins at 20 gestational weeks in a 31- year-old woman without any previous ultrasound examination. The couple decided for pregnancy termination. The formalin-fixed fetuses underwent full-body CT, MRI, and autopsy. Results: ultrasound accurately diagnosed ischiopagus twins. CT was very accurate in the description of bone components. MRI allowed better visualization of the visceral organs than CT. Only autopsy could disclose the aspect of the two gastrointestinal tracts and the external genitalia. Conclusions: Prenatal ultrasound represents the standard diagnostic exam for conjoined twins. CT-MRI virtual autopsy (virtopsy) may be an option if the couple refuses to authorize necropsy or may be useful to plan a minimally invasive autopsy preserving the external phenotype.
Key words:  Autopsy      Computed tomography      Conjoined twins      Magnetic resonance imaging      Ultrasound      Virtopsy     
Published:  10 April 2017     
*Corresponding Author(s):  P. SALA     E-mail:  paolsala@gmail.com

Cite this article: 

M.P. Biso, P. Sala, V.G. Vellone, G. Minetti, C.R. Gaggero, M. Foppiano, E. Fulcheri, P. De Biasio. Virtopsy in conjoined ischiopagus twins. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 288-291.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3385.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I2/288

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