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Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (2): 200-202    DOI: 10.12891/ceog3283.2017
Original Research Previous articles | Next articles
Changes in irisin levels in patients with hyperemesis gravidarum
E.C. Kavak1, S.B. Kavak1, *(), R. Ilhan1, S. Kaplan1, H. Bagci1, M. Kaya2
1 Firat University, School of Medicine, Firat Medical Center, Department of Obstetrics and Gynecology, Elazig, Turkey
2 Special In Vitro Lab, Department of Biochemistry, Elazig, Turkey
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Abstract  
Purpose: The aim of this study was to compare levels of serum irisin in hyperemesis gravidarum (HG) patients to healthy gravidas. Materials and Methods: Twenty pregnant women with hyperemesis gravidarum (Group 1) and 20 healthy pregnant women (Group 2) all of similar ages, body mass index, and all at similar pregnancy development comprised the study cohort. Fasting serum samples were obtained and measured for irisin levels. Comparisons between groups were done by Mann Whitney U (MWU) test and p < 0.05 was considered as statistically significant. Results: All the patients in groups 1 and 2 were primigravid and age, gestational week, and body mass index values were similar. No statistically significant difference were present among these parameters (p > 0.05, MWU test). The plasma irisin concentrations in group 1 were significantly higher (irisin (average ±S D): 116.9 ± 32.3 ng/ml vs. 87.7 ± 26.2 ng/ml) compared to the control group. Conclusion: This study suggests a possible role of irisin, which might be involved in the pathology of HG.
Key words:  Hyperemesis gravidarum      Primigravida      Irisin     
Published:  10 April 2017     
*Corresponding Author(s):  S.B. KAVAK     E-mail:  burcinkavak1@gmail.com

Cite this article: 

E.C. Kavak, S.B. Kavak, R. Ilhan, S. Kaplan, H. Bagci, M. Kaya. Changes in irisin levels in patients with hyperemesis gravidarum. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 200-202.

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https://ceog.imrpress.com/EN/10.12891/ceog3283.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I2/200

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