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Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (2): 177-179    DOI: 10.12891/ceog3218.2017
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Chromosomal microarray analysis in prenatal diagnosis
Yingjun Xie1, Xiaofang Sun1, *()
1 Key Laboratory for Major Obstetric Diseases of Guangdong Province, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Abstract  
Genome copy number variation (CNV) is an important cause of genetic and developmental disorders. In recent years, chromosomal microarray analysis (CMA) technology to test for genomic copy number variation has been developed and gradually applied in prenatal diagnostics, offering high diagnostic ability. Here, the authors summarise the CMA established in clinical settings, as well as the significance and clinical application of the standard analyses. They also emphatically discuss the key problems in the establishment process of the platform in prenatal diagnostics in the clinic.
Key words:  Genome copy number variation      Chromosomal microarray analysis      Prenatal diagnosis      Detection platform     
Published:  10 April 2017     
*Corresponding Author(s):  XIAOFANG SUN     E-mail:  xiaofangsun@hotmail.com

Cite this article: 

Yingjun Xie, Xiaofang Sun. Chromosomal microarray analysis in prenatal diagnosis. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 177-179.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3218.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I2/177

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