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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (5): 831-832    DOI: 10.12891/ceog4808.2019
Case Report Previous articles | Next articles
Pulmonary lymphangioleiomyomatosis as an uncommon cause of recurrent early pregnancy loss
E.H. Comert1, H. Sal1, E.S. Guvendag Guven1, S. Guven1, *()
1Department of Obstetrics and Gynecology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
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Pulmonary lymphangioleimyomatosis (LAM) is a rare disorder characterized by hamartomatous proliferation of smooth muscle within lung parenchyma. LAM occurs only in women and exacerbates with menstruation, estrogen use, and taking oral contraceptives. The effect of pulmonary LAM on recurrent pregnancy loss has not been reported previously. A 28-years-old (gravida 2 parity 0 abortion 2) woman was admitted to the gynecology outpatient clinic because of habitual abortion. The patient had a history of early (one 8-week and another 6-week) pregnancy losses. CT scan showed widespread and varied dimension thin edge cystic lesions extending to about 1 cm in diameter of the largest size observed in all segments of both lungs. All other recurrent pregnancy loss tests were within normal limits, except pulmonary LAM findings on CT scan. Clinicians should keep in mind the diagnosis of pulmonary LAM, in cases with progressive dyspnea (especially in luteal phase of menstruation) and recurrent pregnancy losses.

Key words:  Fibronectin      Habitual abortion      Invasion      Pulmonary lymphangioleiomyomatosis     
Published:  10 October 2019     
*Corresponding Author(s):  S. GUVEN     E-mail:

Cite this article: 

E.H. Comert, H. Sal, E.S. Guvendag Guven, S. Guven. Pulmonary lymphangioleiomyomatosis as an uncommon cause of recurrent early pregnancy loss. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 831-832.

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