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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (5): 709-712    DOI: 10.12891/ceog4608.2019
Original Research Previous articles | Next articles
Pregnancy success rate at recurrent implantation failure patients after hysteroscopic endometrial injury: preliminary study
E.G. Aydeniz1, *(), U. Sari1, T.U.K. Dilek2
1Acibadem Mehmet Ali Aydinlar University Atakent Hospital, Obstetrics and Gynecology Clinic, Infertility Section, Istanbul, Turkey
2Acibadem Mehmet Ali Aydinlar University School of Medicine, Department of Obstetrics&Gynecology, Istanbul, Turkey
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Abstract  

Purpose of Investigation: To assess better implantation and pregnancy rates following endometrial injury in the presence of previous implantation failure, through a retrospective study in a tertiary University Clinic. The aim of this study is to assess improved embryo implantation after hysteroscopic fundal endometrial injury in repeated implantation failure in patients. Materials and Methods: Twenty-nine women who had recurrent implantation failure participated in the study. They had three or more implantation failures with good quality embryo. Anti-Mullerian hormone (AMH) levels, age, antral follicle count, body mass index, and FSH levels were collected. Frozen/thawed embryos (FTE) were transferred in all subjects. Before embryo transfer the authors performed hysteroscopic endometrial injury by micro cold knife. Results: Median age was 38.62 ± 2.47 years in the study. AMH levels changed between 0.35 and 3.8 ng/ml. The pregnancy rate following hysteroscopy: 17 (58,6%) were pregnant and 12 of 29 subjects did not become pregnant. The women who became pregnant following hysteroscopy were younger and had a higher antral follicle count than the non-pregnant women (p = 0.030 and p = 0.0017 respectively; p < 0.05). Conclusion: The endometrial injury before frozen-thawed embryo transfer had a positive effect on patients who had previous recurrent implantation failure.

Key words:  Recurrent implantation failure      In-vitro fertilization      Infertility      Local endometrial injury      Clinical pregnancy rate     
Published:  10 October 2019     
*Corresponding Author(s):  E.G. AYDENIZ     E-mail:  gynelifaygun@gmail.com

Cite this article: 

E.G. Aydeniz, U. Sari, T.U.K. Dilek. Pregnancy success rate at recurrent implantation failure patients after hysteroscopic endometrial injury: preliminary study. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 709-712.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog4608.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I5/709

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