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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (3): 423-426    DOI: 10.12891/ceog4794.2019
Original Research Previous articles | Next articles
Cytogenetic analysis of miscarriage materials of couples with recurrent pregnancy loss in a tertiary center
H. Akin1, E. Karaca1, I. Hortu2, *(), H. Bolat1, Z. Cengisiz1, M. Kazandi2, B. Durmaz1, A. Aykut1, A. Durmaz1, O. Cogulu1
1Department of Medical Genetics, Ege University School of Medicine, Izmir, Turkey
2Department of Obstetrics and Gynecology, Ege University School of Medicine, Izmir, Turkey
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Abstract  

A pregnancy loss (miscarriage) is defined as the spontaneous demise of a pregnancy before the fetus reaches viability. The term therefore includes all pregnancy losses from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss (RPL) is defined as two or more losses of the pregnancy. There are many proposed reasons; however in a prominent portion of cases, the reason remains unclear. Chromosomal abnormalities have an important place in recurrent pregnancy loss. Numerical and structural abnormalities constitute a significant cause. The purpose of this study was to assess the chromosomal abnormality of 490 chorionic villus samples of the couples who experienced RPL and to provide data for both clinicians and genetic counsellors.

Key words:  Recurrent pregnancy loss      Abortion      Cytogenetic abnormalities     
Published:  10 June 2019     
*Corresponding Author(s):  I. HORTU     E-mail:  ismethortu@yahoo.com

Cite this article: 

H. Akin, E. Karaca, I. Hortu, H. Bolat, Z. Cengisiz, M. Kazandi, B. Durmaz, A. Aykut, A. Durmaz, O. Cogulu. Cytogenetic analysis of miscarriage materials of couples with recurrent pregnancy loss in a tertiary center. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 423-426.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog4794.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I3/423

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