Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (1): 118-122    DOI: 10.12891/ceog4152.2019
Original Research Previous articles | Next articles
Effect of differential endometrial injury timing on frozen-thawed embryo transfer pregnancy outcomes
Jianping Zhang1, Fang Yang1, Yaoqin Wang1, Yonglian Wang1, Hongmei Liang1, Xueqing Wu1, *()
1 Gynecology and Obstetric Center, Shanxi Women & Children’s Hospital, Taiyuan, Shanxi, China
Download:  PDF(238KB)  ( 180 ) Full text   ( 6 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Objective: To explore whether differential endometrial injury (EI) timing prior to a frozen-thawed embryo transfer (FET) cycle yields similar improvements in pregnancy outcomes. Materials and Methods: A total of 688 women underwent consecutive FET cycles. Based on their desire to undergo differentially timed EI or not, patients were divided into four groups: on the 3rd –5th day of the menstrual phase of the FET cycle (n = 308), on the 3rd –5th day of the menstrual phase preceding the FET cycle (n = 78), during the luteal phase of the cycle preceding the FET cycle (n = 83), and no intervention (n = 219). Results: The pregnancy outcomes in the four groups were significantly different. The chemical pregnancy, clinical pregnancy, implantation, and live birth rates of patients who underwent EI on the 3rd –5th day of the menstrual phase preceding the FET cycle were the highest, followed by those who underwent EI on the 3rd –5th day of the menstrual phase of the FET cycle. The lowest rates were those during the luteal phase of the cycle preceding the FET cycle and patients who had no interventions, which were similar. Conclusions: Differential EI timing resulted in differential improvement of pregnancy outcomes for FET.
Key words:  Endometrial biopsy      Endometrial injury      Frozen embryo transfer      Implantation      Pregnancy rate.     
Published:  10 February 2019     
*Corresponding Author(s):  XUEQING WU     E-mail:  hyacinth0412@163.com

Cite this article: 

Jianping Zhang, Fang Yang, Yaoqin Wang, Yonglian Wang, Hongmei Liang, Xueqing Wu. Effect of differential endometrial injury timing on frozen-thawed embryo transfer pregnancy outcomes. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(1): 118-122.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog4152.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I1/118

[1] M. Elmahdy, I. Elfourtia, H. Maghraby. Office hysteroscopy in cases of recurrent implantation failure; Do or not to do[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 723-728.
[2] Sh. Gaafar, T. Hanafy, S. El Morshedy, H. Mansour. Effect of extended embryo culture after thawing on clinical pregnancy rate[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 764-768.
[3] M.S. Jo, H.J. Lee, Y.J. Lee, S.C. Kim, J.K. Joo, K.S. Lee. Which is the safer method for trophectoderm biopsy in mouse blastocyst, mechanical or laser?[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(1): 27-30.
[4] E.G. Aydeniz, U. Sari, T.U.K. Dilek. Pregnancy success rate at recurrent implantation failure patients after hysteroscopic endometrial injury: preliminary study[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 709-712.
[5] J. He, L. Zou, L. Wang, S. Zhuang. Effects of regulatory T cells, natural killer cells, and natural killer T cells on immunosuppression therapy in patients with recurrent embryo implantation failure[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 606-610.
[6] J.H. Check, D. Summers, D. Horwath, J.K. Choe. Preimplantation genetic diagnosis for a single gene mutation for succinate dehydrogenase subunit B (the genetic basis for malignant paraganglioma) with successful pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 473-475.
[7] Turgut Aydin, Huseyin Aksoy, Ozge Idem Karadag, Ulku Aksoy, Elif Cinar. A comparative study on therapeutic outcomes and clinical implications of transvaginal and transabdominal guidance during embryo transfer[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 823-827.
[8] J.H. Check. The pros and cons of the requirement by the Society for Assisted Reproductive Technology (SART) for their members who perform in vitro fertilization and related procedures to report their pregnancy rates to the center for disease control[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(2): 155-158.
[9] S.A. Hebeisha, F.S. Moiety, M. Samir, M. Hussein. Effect of endometrial injury on implantation and pregnancy rates: a randomised controlled trial[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(1): 105-108.
[10] J. H. Check, R. Cohen. A second successful pregnancy using oocytes from a woman with premature ovarian failure with embryos transferred to a gestational carrier[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(4): 507-508.
[11] J. Kojima, H. Ito, Y. Thapa, E. Hasegawa, N. Kuji, K. Isaka. Isoflavone increases the mRNA expression levels of IL-6 signal transducer glycoprotein 130 in human endometrial glandular cells[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(4): 572-576.
[12] L. Xie, Y. Wang, Y.C. Man, F.Y. Luo. Preliminary experience in uterine artery embolization for second trimester pregnancy induced labor with complete placenta previa, placenta implantation, and pernicious placenta previa[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(1): 81-84.
No Suggested Reading articles found!