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Clinical and Experimental Obstetrics & Gynecology  2018, Vol. 45 Issue (2): 257-261    DOI: 10.12891/ceog3889.2018
Original Research Previous articles | Next articles
Clinical characteristics and pregnancy outcomes in parturients with pulmonary hypertension: experience with 39 consecutive cases from China
W.Y. Gong1, *(), Y.P. Li1, C.T. Zuo1, X.T. Wang1
1 Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China
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Abstract  
Purpose: The authors aimed to understand the clinical characteristics of pulmonary hypertension (PH) with pregnancy and pregnancy outcomes in Chinese population. Materials and Methods: The authors retrospectively analyzed 39 parturients with PH. The patients were divided into mild PH group (n = 20) and severe PH group (n = 19). They compared some clinical characteristics, as well as maternal and fetal outcomes between the mild and severe PH groups. Results: The diagnostic rate of PH before pregnancy was 7.7% and the overall maternal mortality was 15.4%. There was no significant difference in age, body mass index, average termination of gestation weeks, and New York Heart Association functional class pre-pregnancy between the mild and severe PH groups. The mortality in the severe PH group (31.6%) was significantly higher than that in the mild PH group (0%) (p < 0. 05). In addition, the occurrence rate of post-partum haemorrhage (PPH) and natality of low-birth weight neonates (LBWN) were significantly higher in the severe PH group (21.1%; 36.8%) than that in the mild PH group (0%; 10%) (p < 0. 05), respectively. Conclusion: The overall mortality of parturients with PH is high and severe PH increase the risk of death, occurrence rate of PPH, and natality of LBWN.
Key words:  Pregnancy      Pulmonary hypertension      Maternal mortality      Post-partum haemorrhage      Low-birth weight neonates     
Published:  10 April 2018     
*Corresponding Author(s):  W.Y. GONG     E-mail:  gweiyanan@hotmail.com

Cite this article: 

W.Y. Gong, Y.P. Li, C.T. Zuo, X.T. Wang. Clinical characteristics and pregnancy outcomes in parturients with pulmonary hypertension: experience with 39 consecutive cases from China. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(2): 257-261.

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https://ceog.imrpress.com/EN/10.12891/ceog3889.2018     OR     https://ceog.imrpress.com/EN/Y2018/V45/I2/257

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