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Clinical and Experimental Obstetrics & Gynecology  2018, Vol. 45 Issue (1): 105-108    DOI: 10.12891/ceog3781.2018
Original Research Previous articles | Next articles
Effect of endometrial injury on implantation and pregnancy rates: a randomised controlled trial
S.A. Hebeisha1, F.S. Moiety1, *(), M. Samir1, M. Hussein1
1 Department of Obstetrics and Gynecology, Faculty of Medicine, University of Alexandria, Alexandria, Egypt
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Abstract  
Objective: To study the effect of induced endometrial injury on the pregnancy and implantation rates in patients undergoing intracytoplasmic sperm injection (ICSI) cycles. Study Design: Randomised case control study. Setting: University hospital's fertility clinic. Materials and Methods: A total of 240 women undergoing ICSI cycles were randomly divided into three equal groups, Group A underwent endometrial scratching by pipelle, group B underwent hysteroscopic endometrial injury, and group C were controls. Results: No difference was seen between the groups in terms of age, BMI, endometrial thickness, number of oocytes retrieved, or number of embryos transferred. Pregnancy rate was similar in groups A and B, which was higher than group C, but the difference was not statistically significant. Implantation rate was significantly higher in both groups A and B than controls, and significantly in group B compared to group A. Conclusions: Endometrial injury, especially if induced by hysteroscopy, might be helpful to increase the implantation rate in cases undergoing ICSI-embryo transfer (ICSI-ET). Pregnancy rate however did not change.
Key words:  Endometrium      Injury      Pregnancy      Implantation     
Published:  10 February 2018     
*Corresponding Author(s):  F.S. MOIETY     E-mail:  fmoiety@gmail.com

Cite this article: 

S.A. Hebeisha, F.S. Moiety, M. Samir, M. Hussein. Effect of endometrial injury on implantation and pregnancy rates: a randomised controlled trial. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(1): 105-108.

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https://ceog.imrpress.com/EN/10.12891/ceog3781.2018     OR     https://ceog.imrpress.com/EN/Y2018/V45/I1/105

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