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Clinical and Experimental Obstetrics & Gynecology  2018, Vol. 45 Issue (1): 68-71    DOI: 10.12891/ceog3745.2018
Original Research Previous articles | Next articles
Changes in serum adropin, salusin alpha and salusin beta, vaspin, and preptin in hyperemesis gravidarum
Z.O. Dag1, *(), O.B. Tulmac1, Y. Isik1, U. Kisa2, S. Aydin3
1 Department of Gynecology and Obstetrics, Kirikkale University, Faculty of Medicine, Kirikkale, Turkey
2 Departments of Biochemistry, Kirikkale University, Faculty of Medicine, Kirikkale, Turkey
3 Departments of Biochemistry, Fırat University, Faculty of Medicine, Elazig, Turkey
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Abstract  
Purpose: To investigate serum levels of adropin, salusin alpha and salusin beta, vaspin, and preptin in pregnant women with hyperemesis gravidarum (HG) and uncomplicated pregnancies. Materials and Methods: Thirty-three pregnant women with HG (group 1) and 30 pregnant women with uncomplicated pregnancies (group 2) who were referred to the University Obstetrics-Gynecology clinic were enrolled in this present study. Fasting serum samples were obtained and measured for adropin, salusin alpha and salusin beta, vaspin, and preptin. The hormones levels were studied by using ELISA method. Results: Statistically significant difference was found between groups 1 and 2 according to adropin, salusin alpha and salusin beta, vaspin, and preptin levels (all p < 0.05). There were increased levels of salusins and adropin and decreased levels of vaspin and preptin in women with HG. Conclusion: This study suggests a possible role of these peptides, which may clarify the etiopathogenesis of HG.
Key words:  Hyperemesis gravidarum      Adropin      Salusin alpha and salusin beta      Vaspin      Preptin     
Published:  10 February 2018     
*Corresponding Author(s):  Z. OZCAN DAG     E-mail:  zozcan23@yahoo.com

Cite this article: 

Z.O. Dag, O.B. Tulmac, Y. Isik, U. Kisa, S. Aydin. Changes in serum adropin, salusin alpha and salusin beta, vaspin, and preptin in hyperemesis gravidarum. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(1): 68-71.

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https://ceog.imrpress.com/EN/10.12891/ceog3745.2018     OR     https://ceog.imrpress.com/EN/Y2018/V45/I1/68

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