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Clinical and Experimental Obstetrics & Gynecology  2018, Vol. 45 Issue (1): 63-67    DOI: 10.12891/ceog3759.2018
Original Research Previous articles | Next articles
Hypothyroidism among subfertile women
D. Al-Jaroudi1, *(), S. Yassin1, N. Al Enezi1, O. Kaddour1, A. Al-Badr1
1 Reproductive Endocrine and Infertility Medicine Department (REIMD), Women's Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia
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Abstract  
Introduction: Association between hypothyroidism and infertility has been demonstrated, but its prevalence in subfertile women is not well documented. Objective: To estimate the prevalence of hypothyroidism in a cohort of subfertile women. Materials and Methods: Retrospective chart of 200 women aged 17 to 40 years with infertility attending the Reproductive Endocrine and Infertility Medicine Department between April 2008 and October 2010 was reviewed. Rate of established or newly diagnosed hypothyroidism was measured, as well as the associations between TSH > 4.2 mIU/L and patient characteristics, causes of infertility, and laboratory parameters. Results: Fourteen percent had established and 14.5% had newly diagnosed hypothyroidism. Subclinical hypothyroidism was determined for 42 (21%) women. Hypothyroidism associated significantly with both increased LH and anovulatory related infertility: LH (8.49 IU/L vs. 6.86 IU/L; p = 0.036) and anovulation in 47.8% vs. 27.3% (p = 0.009) of women with TSH > 4.2 mIU/L and TSH ≤ 4.2 mIU/L, respectively. Conclusion: This study confirms an association between hypothyroidism and infertility and highlights the need to check thyroid hormone levels prior to infertility treatment.
Key words:  Hypothyroidism      Infertility      Retrospective      Prevalence     
Published:  10 February 2018     
*Corresponding Author(s):  D. AL-JAROUDI     E-mail:  daljaroudi@kfmc.med.sa

Cite this article: 

D. Al-Jaroudi, S. Yassin, N. Al Enezi, O. Kaddour, A. Al-Badr. Hypothyroidism among subfertile women. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(1): 63-67.

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https://ceog.imrpress.com/EN/10.12891/ceog3759.2018     OR     https://ceog.imrpress.com/EN/Y2018/V45/I1/63

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