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Clinical and Experimental Obstetrics & Gynecology  2018, Vol. 45 Issue (6): 837-841    DOI: 10.12891/ceog4212.2018
Original Research Previous articles | Next articles
Maternal and perinatal outcomes in early onset and late onset preeclampsia
A. Simsek1, *(), S. Uludag1, A. Tuten1, A. S. Acikgoz1, S. Uludag1
1 Istanbul University, Cerrahpasa School of Medicine, Department of Obstetric and Gynecology, Istanbul, Turkey
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Abstract  
Purpose: This study was performed to compare the clinical findings and identify differences in risk factors between early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE). Materials and Methods: This retrospective study included 516 women with singleton pregnancies and preeclampsia (none of them had superimposed preeclampsia on chronic hypertension) who delivered in a tertiary care center. Clinical findings, and maternal and perinatal outcomes were compared between early (< 34 weeks’ gestation) and late (≥ 34 weeks’ gestation) onset of the disease. Results: Incidences of nulliparity, previous preterm births, stillbirths, and first trimester abortions were significantly higher in women with EO-PE (p < 0.05). History of disease other than chronic hypertension (especially diabetes mellitus) and previous term births were significantly higher in women with late-onset disease (p < 0.05). The mean gestational week at delivery and mean birth weight were significantly lower in early-onset disease (p < 0.05). Stillbirths, early and late neonatal deaths, and cases where the mother’s life at risk were significantly higher in women with early-onset disease (p < 0.05). Conclusions: EO-PE appears to be mediated by the placenta and associated with higher incidence of perinatal, neonatal and maternal deaths, and maternal nearmiss cases.
Key words:  Preeclampsia      EO-PE, LO-PE      Maternal mortality      Perinatal mortality     
Published:  10 December 2018     
*Corresponding Author(s):  A. SIMSEK     E-mail:  draksimsek@yahoo.com.tr

Cite this article: 

A. Simsek, S. Uludag, A. Tuten, A. S. Acikgoz, S. Uludag. Maternal and perinatal outcomes in early onset and late onset preeclampsia. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 837-841.

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https://ceog.imrpress.com/EN/10.12891/ceog4212.2018     OR     https://ceog.imrpress.com/EN/Y2018/V45/I6/837

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