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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (3): 631-636    DOI: 10.31083/j.ceog.2021.03.2450
Special Issue: Caesarean Section Today - “Caesarology in the 21st Century”
Original Research Previous articles | Next articles
Perinatal outcome in twins. A hospital based comparative study at a single third-level care centre in Croatia
Dino Pavoković1, *(), †, Vesna Elveđi Gašparović2, 3, *(), †, Tvrtko Tupek4, Analena Gregorić5, Ana Tikvica Luetić4, 6, †, Dubravko Habek4, 6
1Department of Obstetrics and Gynaecology, General Hospital Virovitica, 33000 Virovitica, Croatia
2Department of Obstetrics and Gynaecology, University Hospital Centre Zagreb, 10000 Zagreb, Croatia
3School of Medicine, University of Zagreb, 10000 Zagreb, Croatia
4Department of Obstetrics and Gynaecology, Clinical Hospital 'Sveti Duh', 10000 Zagreb, Croatia
5Department of Obstetrics and Gynaecology, General Hospital Karlovac, 47000 Karlovac, Croatia
6School of Medicine, Catholic University of Croatia, 10000 Zagreb, Croatia
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Abstract  
Background: The goal of our study is to explore the association of assisted reproductive technology (ART) as contributing factor for obstetric complications and perinatal outcome in twin pregnancies during a 14-year period at a single tertiary centre. Methods: We collected the data (from maternal and neonatal medical records) from 731 twin pregnancies; 192 conceived by ART and 539 twin pregnancies conceived naturally during a 14-year period. Results: Pregnancy complications in twin pregnancies mainly included preterm premature rupture of membranes, gestational diabetes mellitus, and preeclampsia. Higher occurrence of placenta praevia in the ART group was the only perinatal risk related to twin pregnancies in the ART group as compared to those conceived naturally. Over 71% of ART twins were delivered by caesarean section, which is considerably increased as compared to non-ART twins (P = 0.042). Neonatal complications in both groups mainly included low Apgar score in the 1st minute, low birth weight and admission to NICU, and the incidences of these complications were comparable between the groups. Conclusion: Our results indicated that ART procedures were not followed by adverse obstetric and perinatal outcome in twin pregnancy delivered at single tertiary centre, except for the slightly higher risk of placenta praevia.
Key words:  Twin pregnancy      Assisted reproductive technology      Obstetric complications     
Submitted:  04 January 2021      Revised:  22 February 2021      Accepted:  04 March 2021      Published:  15 June 2021     
*Corresponding Author(s):  pavokovic@hotmail.com (Dino Pavoković); vesnagasparo@gmail.com (Vesna Elveđi Gašparović)   
About author:  These authors contributed equally.

Cite this article: 

Dino Pavoković, Vesna Elveđi Gašparović, Tvrtko Tupek, Analena Gregorić, Ana Tikvica Luetić, Dubravko Habek. Perinatal outcome in twins. A hospital based comparative study at a single third-level care centre in Croatia. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 631-636.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.03.2450     OR     https://ceog.imrpress.com/EN/Y2021/V48/I3/631

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