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Clinical and Experimental Obstetrics & Gynecology  2020, Vol. 47 Issue (5): 741-743    DOI: 10.31083/j.ceog.2020.05.5373
Original Research Previous articles | Next articles
Seroprevalence of Dengue virus among pregnant mothers and their-newborn infants in the southwest of Saudi Arabia
Ali S. Alqahtani1, *()
1Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran, 1988, Kingdom of Saudi Arabia
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Dengue virus (DENV) is one of the most serious arthropod-borne viruses. This study was performed to investigate the prevalence of the virus in Najran, a city in the south west of Saudi Arabia. Four hundred and ten paired maternal and umbilical serum samples were obtained from mothers and their newborn infants. The samples were tested for the presence of IgG antibodies by ELISA. Anti-DENV IgG antibodies were detected in 31 maternal samples (7.6%), while all newborn samples were negative. All maternal seropositive samples were negative when tested by PCR. These results are further indication that DENV is endemic in Saudi Arabia and enhanced DENV surveillance is necessary.

Key words:  Dengue      ELISA      PCR      Serum      Saudi Arabia      Pregnancy      Newborn infants     
Submitted:  15 September 2019      Accepted:  07 November 2019      Published:  15 October 2020     
*Corresponding Author(s):  Ali S. Alqahtani     E-mail:

Cite this article: 

Ali S. Alqahtani. Seroprevalence of Dengue virus among pregnant mothers and their-newborn infants in the southwest of Saudi Arabia. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 741-743.

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Table 1  — Demographic and clinical characteristics of the mothers.
Variables Total N (%) DENV IgG positive
N (%)
Residency In Najran 342 (83.4) 29 (8.5)
Out of Najran 68 (16.6) 2 (2.9)
History of travel Yes 35 (8.5) 0 (0)
No 375 (91.5) 31 (8.3)
Temperature 37 407 (99.3) 31 (7.6)
> 38 ℃ 3 (0.7) 0 (0)
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