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Clinical and Experimental Obstetrics & Gynecology  2020, Vol. 47 Issue (4): 620-621    DOI: 10.31083/j.ceog.2020.04.5178
Case Report Previous articles |
A case report supporting the concept that a role for the anti-Müllerian hormone (AMH) in normal folliculogenesis is to diminish the biological activity of follicle stimulating hormone (FSH)
J.H. Check1, 2, *(), E. Chang1, 2, R. Cohen1, 2
1Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, United States
2Cooper Institute for Reproductive Hormonal Disorders, P.C., Mt. Laurel, NJ, United States
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Abstract  
Purpose: To describe a case where a woman was ovulating with regular menses despite very low sera follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels. Case Report: Serum anti-Müllerian (AMH) was obtained because the woman was to be an egg donor for her identical twin sister. This 28-year-old woman responded fairly well to controlled ovarian hyperstimulation producing ten metaphase II eggs and eight fertilized and were cryopreserved on day 3. Her serum AMH level was subnormal at 0.6 ng/mL. Conclusions: This case suggests that FSH may be more biologically active in the presence of low AMH.
Key words:  Decreased oocyte reserve      Anti-Müllerian hormone      Gonadotropin deficiency      FSH induced aromatase enzyme     
Submitted:  12 March 2019      Accepted:  02 May 2019      Published:  15 August 2020     
*Corresponding Author(s):  JEROME H. CHECK     E-mail:  laurie@ccivf.com

Cite this article: 

J.H. Check, E. Chang, R. Cohen. A case report supporting the concept that a role for the anti-Müllerian hormone (AMH) in normal folliculogenesis is to diminish the biological activity of follicle stimulating hormone (FSH). Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 620-621.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2020.04.5178     OR     https://ceog.imrpress.com/EN/Y2020/V47/I4/620

[1] H. Saleh, F. Moiety, A.F. Agameya, Y. Elkassar, R.M. El Sharakwy, D. Zeidan, H. Elmeligy. Comparison between antral follicle count and anti-Müllerian hormonal level in the prediction of ovarian response and pregnancy outcome in intracytoplasmic sperm injection patients: implications in personalizing ovarian stimulation[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 166-173.
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