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Clinical and Experimental Obstetrics & Gynecology  2020, Vol. 47 Issue (2): 253-256    DOI: 10.31083/j.ceog.2020.02.5193
Original Research Previous articles | Next articles
Candida albicans infection of cervix and comparison of Pap smear and culture in diagnosis
T. Cengiz1, T. Toka Özer2, *(), F. Kılınç3, R. Selimoğlu4, H. Yılmaz5
1Department of Obstetrics and Gynecology, Ortadoğu Hospital, Adana, Turkey
2Department of Medical Microbiology, Konya Hospital, Konya, Turkey
3Department of Pathology, Medical Faculty, Necmettin Erbakan University, Konya, Turkey
4Department of Medical Microbiology, Anıt Hospital, Konya, Turkey
5Department of Obstetrics and Gynecology, Şemdinli State Hospital, Hakkari, Turkey
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Purpose: The Pap smear is a routine screening test for the detection of cervical abnormalities viral, bacterial, and fungal infections of the uterine cervix, The aim of this study is to investigate if Pap smear is an alternative to cervicovaginal culture in the diagnosis of asymptomatic Candida. Materials and Methods: A retrospective analysis of 133 non-pregnant asymptomatic cases were included. Candida spp. positive cases in Pap smear and/or culture were compared. Results: Candida spp. was found in 45 cases in culture and 40 cases of Candida in Pap smear examination. The sensitivity of Pap smear was 88%, specificity was 100%, the positive predictive value was 100%, the negative predictive value was 94%, and the overall power of the test (test validity) was 96%. It was detected that 33.83% of the asymptomatic cases had Candida infection. Conclusion: Pap smear can be used as a first-line examination method.

Key words:  Pap smear      Candida infections      Cervicovaginal culture      Sabourad dextrose agar      Screening test     
Published:  15 April 2020     
*Corresponding Author(s):  T. Toka ?zer     E-mail:

Cite this article: 

T. Cengiz, T. Toka Özer, F. Kılınç, R. Selimoğlu, H. Yılmaz. Candida albicans infection of cervix and comparison of Pap smear and culture in diagnosis. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 253-256.

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Figure 1.  Candida in Pap smear.

Table 1  — Distribution of Candida detected cases by both methods according to age groups.
(Group1) (Group2) (Group 3) Total
Age groups

Number of cases in groups 67 (50.38) 53(39.85) 13(9.77) 133(100.00)
Pap smear-Candida (+) 28 (70) 11(27.50) 1(2.5) 40(30.08)
Culture-Candida (+) 31(68.89) 12(26.67) 2 (4.44) 45(33.83)
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