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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (2): 327-330    DOI: 10.12891/ceog4562.2019
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Ectopic prostatic tissue in vagina - case report
V. Pažin1, A. DobrosavljeviĆ2, *(), J. ŠtuliĆ2, M. CimbaljeviĆ2
1Faculty of Medicine, University of Belgrade, Doktora SubotiĆa 8; Clinic of Obstetrics and Gynecology “Narodni Front”, Belgrade, Serbia;
2Clinic of Obstetrics and Gynecology “Narodni Front”, Belgrade, Serbia;
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During embryonic development, both glandular parenchyma of prostate in a male fetus and paraurethral Skene’s glands in a female fetus develop from pelvic urethra endoderm. This common embryological origin results in finding prostatic tissue even in the lower genital tract in women. Herein, the authors present a case of polypoid lesion in vagina consisting solely of glandular elements without squamous component, which stained negative for prostatic markers, but morphologically identical to normal prostatic tissue. A patient, 57-years-old came to the Clinic, with a cystic change in the petiole, which size being 30×17×15 mm, on the left vaginal wall adjacent to introitus. The cystic change was excised and a preparation was sent to a histopathological examination. The histopathological examination included serial Hematoxylin and Eosin stained sections, along with immunohistochemical panel. It was concluded that it was ectopic prostatic tissue or ectopic paraurethral gland tissue within vaginal mucosa. Partially, epithelium at the surface of our polypoid lesion showed immature squamous metaplasia, vaginal intraepithelial neoplasia - VaIN II/III, and transitional cell metaplasia. Gland formations having benign features were within base of the change, at the resection lines, while dysplastic epithelium was fully removed.

Key words:  Vaginal tubulosquamous polyp      Skene’s glands;      Ectopic prostatic tissue     
Published:  10 April 2019     
*Corresponding Author(s):  A. DOBROSAVLJEVIĆ     E-mail:

Cite this article: 

V. Pažin, A. DobrosavljeviĆ, J. ŠtuliĆ, M. CimbaljeviĆ. Ectopic prostatic tissue in vagina - case report. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 327-330.

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