Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (6): 834-838    DOI: 10.12891/ceog3690.2017
Original Research Previous articles | Next articles
Prenatal diagnosis of absent pulmonary valve syndrome: results of a single-center experience in Beijing
J. Han1, X. Liu1, Y. Zhao1, Y. Zhang1, L. Sun1, X. Gu1, X. Yang1, Y. Li2, Y. He1, *()
1 Department of Ultrasound, Beijing Anzhen Hospital, Capital Medical University; Beijing Key Laboratory of Maternal-Fetus Medicine in Fetal Heart Disease, Beijing, China
2 Department of General Surgery and The Center for Fetal Research, The Children's Hospital of Philadelphia, Philadelphia, USA
Download:  PDF
Export:  BibTeX | EndNote (RIS)      
Abstract  
Objective: The purpose of this study was to analyze the fetal echocardiographic features of absent pulmonary valve syndrome (APVS). Materials and Methods: Echocardiographic findings were retrospectively analyzed and summarized in nine fetuses with APVS. Results: The right ventricle was dilated in six cases (66.7%). The cardiac axis was abnormally deviated to the left in four cases (44.4%). The pulmonary valve was either absent or rudimentary in all cases. The main pulmonary artery or its branches were significantly dilated. Color Doppler flow imaging showed severe pulmonary regurgitation. Spectral Doppler imaging showed stenosis of the pulmonary annulus in seven cases. Seven cases were associated with tetralogy of Fallot, two with right aortic arch, two with double outlet right ventricle, and one with mitral valve atresia and single ventricle of right ventricular type. Conclusions: Presence of a markedly dilated right ventricle and pulmonary arteries, combined with stenosis and severe regurgitation of the pulmonary annulus should be considered as APVS.
Key words:  Fetal echocardiography      Absent pulmonary valve      Prenatal diagnosis     
Published:  10 December 2017     
*Corresponding Author(s):  YIHUA HE     E-mail:  yihuaheecho@163.com

Cite this article: 

J. Han, X. Liu, Y. Zhao, Y. Zhang, L. Sun, X. Gu, X. Yang, Y. Li, Y. He. Prenatal diagnosis of absent pulmonary valve syndrome: results of a single-center experience in Beijing. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(6): 834-838.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3690.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I6/834

[1] Thanakorn Heetchuay, Thotsapon Trakulmungkichkarn, Noel Pabalan, Nutthaphon Imsom-Somboon. Reference values of fetal atrioventricular time intervals derive from antegrade late diastolic arterial blood flow (ALDAF) from 14 to 40 weeks of gestation[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(4): 867-874.
[2] Saša Raičević, Duško Kljakić, Filip Vukmirović, Miloš Z. Milosavljević. A giant placental chorioangioma with a resultant live birth; a discussion of management options[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 426-430.
[3] Suchaya Luewan, Pakorn Chaksuwat, Tip Pongsuvareeyakul, Theera Tongsong. Prenatal sonographic findings and management of placental mesenchymal dysplasia[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 439-443.
[4] Sureyya Saridas Demir, Erkan Cağliyan, Sabahattin Altunyurt. Retrospective analysis of pregnancy terminations and indications in a tertiary center[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 85-90.
[5] Y.J. Wu, C.J. Yu, W.H. Tian, Z. Xu. Prenatal diagnosis and molecular cytogenetic characterization of two hereditary chromosomal duplications with favorable outcomes[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 789-791.
[6] B.F. Zhou, C.X. Duan, D.L. Tang. Methylmalonic acidemia in prenatal diagnosis[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 617-619.
[7] D. Lu, D. Cao, Q. Zhao, X. Chen. Prenatal diagnosis and genetic counseling of mosaicism for chromosome t (7; 14) with a favorable outcome[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 427-428.
[8] W. B. Wang, Q. Wu, Y. Zhou, X. Zhong, Y. Ge, J. Zhang. A 10-year retrospective study on prenatal cytogenetic analyses[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 248-252.
[9] Q.C. Wu, W.B. Wang, L. Sun, Y.S. Xu, X.J. Xie, X.M. Ma, Z.Y. Su. Mutation analysis of the fibroblast growth factor receptor 3 gene in fetuses with thanatophoric dysplasia, type I[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(1): 7-11.
[10] G. Szabó, J. Rigó Jr.. Prenatal ultrasound diagnosis of abdominal pregnancy of ovarian origin[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 977-979.
[11] D. Matsubara, H. Takahashi, K. Kataoka, T. Minami, R. Furukawa, S. Matsubara, T. Yamagata. Tracheal stenosis due to vascular rings: its possible prenatal diagnosis based on four cases of vascular rings with or without eventual tracheal stenosis[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 828-830.
[12] W. Homola, M. Zimmer. Safety of amniocentesis in normal pregnancies and pregnancies considered high-risk due to fetal genetic anomalies - an observational study[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 403-407.
[13] D.Y. Ma, G. Liu, C.Y. Luo, A. Liu, J.J. Zhang, P. Hu, J. Cheng, Y.G. Wang, T. Jiang, J.F. Xu. A novel mutation in the mutations in the methyl-CpG-binding protein 2 (MECP2) gene in a Chinese patient with typical Rett syndrome and subsequent prenatal diagnosis[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 924-929.
[14] S. G. Erzincan, N. C. Sayin, C. Inan, M. A. Yuce, F. G. Varol, S. Basaran. Cell-free DNA testing: is it reliable? A case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 939-941.
[15] Bo Wang, Dan Lu, Zuliang Shi, Jian Ke, Qi Zhao, Hongjun Li. Prenatal diagnosis of a complex chromosomal rearrangement involving five chromosomes[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(5): 797-799.
No Suggested Reading articles found!