Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2017, Vol. 44 Issue (5): 710-715    DOI: 10.12891/ceog3744.2017
Original Research Previous articles | Next articles
Uterus and myoma histomorphology
İ. Ceylan1, T. Peker2, *(), N. Coşkun3, S. Ömeroğlu3, A. Poyraz4
1 Ankara University, Institute of Health, Neuroscience Department, Sihhiye, Ankara, Turkey
2 Department of Anatomy, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey
3 Department of Histology and Embryology, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey
4 Department of Pathology, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey
Download:  PDF(2317KB)  ( 67 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Objective: Uterine fibroids, or leiomyomas are common benign neoplasms of the myometrium. These neoplasms are composed of large amounts of extracellular matrix and disarrayed smooth muscle tissue. The aim of this study was to examine the histomorphological differences between myoma uteri and uterus. Materials and Methods: Thickness of muscle fascicles and collagen fibers, and vascular and histological structures were evaluated by using morphometric, histomorphologic and immunohistochemical analyses, and findings represented by using three-dimensional (3D) modeling. The authors used a light microscope and photos were captured using a specific program for analysis. Light micrographs were assembled into 3D images. Results and Conclusion: Histological and 3D findings demonstrated that the muscle fiber is a vital part of the myometrium and loss of its contractility indicates a significant deviation from the uterine structure.
Key words:  Histomorphology      Immunohistochemistry      Three-dimensional modeling      Uterine myoma      Uterus      Leiomyomas     
Published:  10 October 2017     
*Corresponding Author(s):  T. PEKER     E-mail:  tpeker@gazi.edu.tr

Cite this article: 

İ. Ceylan, T. Peker, N. Coşkun, S. Ömeroğlu, A. Poyraz. Uterus and myoma histomorphology. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(5): 710-715.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog3744.2017     OR     https://ceog.imrpress.com/EN/Y2017/V44/I5/710

[1] Ji-Chen Wang, De-Ying Wei, Chen Su, Qi Han, Yong-Hao Gai. Intraoperative management of a Robert's uterus without hematometra in blind hemi-cavity preoperatively misdiagnosed as septate uterus[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1219-1223.
[2] Basilio Pecorino, Giuseppe Scibilia, Placido Borzì, Maria Elena Vento, Pierfrancesco Veroux, Paolo Scollo. Diminished ovarian reserve and ectopic ovaries in patients with Mayer-Rokitansky-Küster-Hauser syndrome candidates for Uterus Transplantation: our experience[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(4): 907-912.
[3] Francesco Fedele, Alessandro Bulfoni, Stefano Salvatore, Massimo Candiani. Fertility options in Mayer-Rokitansky-Küster-Hauser syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 453-460.
[4] Li-Min Zhou, Jie Duan, Yan Yang. Endoscopic treatment with concomitant ultrasound monitoring of obstructive septum in Robert's uterus following pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 711-714.
[5] Saša Raičević, Duško Kljakić, Filip Vukmirović, Miloš Z. Milosavljević. A giant placental chorioangioma with a resultant live birth; a discussion of management options[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 426-430.
[6] Khac Tu Chau, Minh Tam Le, Doan Tu Tran, Vu Quoc Huy Nguyen. Uterine torsion in a 25-week pregnant female with congenital uterine didelphys and intraoperative complication of uterine atony: a report of a rare clinical case[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 185-188.
[7] L. Lamprou, G. Panagopoulou, N. Papadopoulos, C. Tsigalou, O. Pagonopoulou, M. Lambropoulou. Impact of chorioamnionitis and other intrauterine pathological conditions on human foetal cytoskeleton structural protein development: An immunohistochemical study[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 856-861.
[8] Y.A. Kim. Mature cystic teratoma of the uterus presenting as an endometrial polyp in a patient with a history of ovarian mature cystic teratoma with gliomatosis peritonei and ovarian endometriosis: a case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 800-804.
[9] M. Minase, T. Miyamoto, N. Hayashi, G. Minase, K. Nishiwaki, K. Sengoku. A patient with a didelphys vaginal septum and infertility diagnosed by laparoscopy and magnetic resonance imaging[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 988-989.
[10] L. Roncati, F. Piscioli. Sudden unexpected post-natal collapse (SUPC) during skin-to-skin care (SSC): where is the trouble?[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 671-673.
[11] E. Fila, U. Indraccolo, M. Pedriali, G. Scutiero, C. Borghi, P. Greco. Histological pattern of leiomyomas after ulipristal acetate treatment in women: a case-control study[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 792-796.
[12] A.M. Coelho Holanda, F. Osório Marques, I.M. Seabra Leite, J.A. dos Santos Junior. Myomectomy in the 14th week of pregnancy - case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 818-820.
[13] Ş. Gezer, B. Vural. Double cervix, septate uterus, and longitudinal vaginal septum: a rare Müllerian anomaly with leiomyoma of the uterus[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 648-650.
[14] I. Rudic Biljic-Erski, M. Vasiljevic, S. Rakic, O. Dzatic-Smiljkovic, S. Mihajlovic, D. Jovanovic. Term pregnancy not requiring cerclage placement or tocolytic therapy in a patient with a unicornuate uterus and history of myomectomy[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(1): 151-153.
[15] C. Theofanakis, L. Michala, A. Karampelas, S.N. Al-Achmar, G. Daskalakis. Second trimester uterine rupture in a septated unscarred uterus: a case report study[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 599-601.
No Suggested Reading articles found!