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Clinical and Experimental Obstetrics & Gynecology  2008, Vol. 35 Issue (3): 179-182    DOI:
Original Research Previous articles | Next articles
Maternal serum mannose-binding lectin in severe preeclampsia
N. Çelik1, H. Ozan1, *()
1Department of Obstetrics and Gynecology, Uludag University Medical Faculty, Bursa (Turkey)
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Abstract  
Purpose: We aimed to investigate the level of serum mannose-binding lectin (MBL) in severe preeclamptic patients, women with uncomplicated pregnancies, and healthy reproductive-age females and its impact on gestational age at delivery and birth weight. Methods: Serum MBL levels were measured in 27 severe preeclampsia patients (Group 1), 27 patients with uncomplicated pregnancies (Group 2), and 25 healthy reproductive-age women (Group 3). Results: The mean serum MBL was significantly higher (p ≤ 0.05) in Group 1 than in Groups 2 and 3, while the levels in Groups 2 and 3 did not significantly differ. The mean gestational age at delivery and mean birth weight were significantly lower in Group 1. In Group 1, serum MBL was negatively correlated (p ≤ 0.05) with the gestational age at delivery and birth weight. Conclusion: Serum MBL increased in preeclampsia and was negatively correlated with the gestational age at birth and birth weight, indicating an underlying immunopathogenesis.
Key words:  Mannose-binding lectin      Preeclampsia     
Published:  10 September 2008     
*Corresponding Author(s):  H. OZAN     E-mail:  hozan@superonline.com

Cite this article: 

N. Çelik, H. Ozan. Maternal serum mannose-binding lectin in severe preeclampsia. Clinical and Experimental Obstetrics & Gynecology, 2008, 35(3): 179-182.

URL: 

https://ceog.imrpress.com/EN/     OR     https://ceog.imrpress.com/EN/Y2008/V35/I3/179

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