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Clinical and Experimental Obstetrics & Gynecology  2008, Vol. 35 Issue (3): 167-169    DOI:
Original Research Previous articles | Next articles
Improved pregnancy outcome for women with decreased ovarian oocyte reserve and advanced reproductive age by performing in vitro fertilization-embryo transfer
J. H. Check1, *(), J. Pinto1, J. R. Liss1, J. K. Choe1
1The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
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Abstract  
Objective: To compare the pregnancy rates with IVF-ET vs non-assisted reproductive technology in women of more advanced reproductive age with decreased egg reserve as manifested by elevated day 3 serum FSH. Methods: A retrospective evaluation was made in women aged ≥ 38 with a day 3 serum FSH of ≥ 15 mIU/mL with ≥ 1 year of infertility. Another inclusion criterion was three cycles (unless a pregnancy occurred before that time) of either IVF-ET or non-assisted reproductive therapy which as a minimum included luteal phase support with progesterone. Results: The clinical pregnancy rates in three cycles for non-IVF were 11.7% vs 27.2% for IVF. Delivery rates were 2.9% vs 15.1%. For ages 40-42 the clinical pregnancy rates were 37.5% vs 0.0% (p =0.02). Conclusions: Live deliveries are possible in women ≥ age 38 with marked decreased egg reserve. In vitro fertilization is more effective than non-IVF when follicle stimulation with gonadotropins is mild.
Key words:  Diminished egg reserve      In vitro fertilization      Minimal stimulation      FSH     
Published:  10 September 2008     
*Corresponding Author(s):  J. H. CHECK     E-mail:  laurie@ccivf.com

Cite this article: 

J. H. Check, J. Pinto, J. R. Liss, J. K. Choe. Improved pregnancy outcome for women with decreased ovarian oocyte reserve and advanced reproductive age by performing in vitro fertilization-embryo transfer. Clinical and Experimental Obstetrics & Gynecology, 2008, 35(3): 167-169.

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https://ceog.imrpress.com/EN/     OR     https://ceog.imrpress.com/EN/Y2008/V35/I3/167

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