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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (5): 1025-1031    DOI: 10.31083/j.ceog4805165
Special Issue: Female infertility and treatment strategies
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Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women
Pelin Kutlu1, *(), Seda Karabulut2, Oya Korkmaz2
1Istanbul Medicana Çamlıca Hospital, IVF Center, 34692 İstanbul, Turkey
2Department of Histology and Embryology, School of Medicine, Istanbul Medipol University, 34815 İstanbul, Turkey
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Abstract  
Objective: There are diverse findings concerning the use of platelet-rich plasma (PRP) in assisted reproduction treatment (ART) cycles of infertile women with low ovarian reserve, ovarian failure or implantation failure due to endometrial problems. A debate continues regarding the benefit of this technique because of the low number of evidence-based studies. Mechanism: Different PRP preparation methods have been described in the literature, aiming to obtain the highest number of platelets following centrifugation steps. Findings in brief: Research on the use of PRP in female infertility aims to improve the deteriorated hormonal profile, gamete production and implantation of the embryo into the endometrium. Conclusions: This paper reviewed literature evaluating the impact of PRP on the outcomes of subsequent ART cycles in infertile women. PRP is a safe and easy-to-apply procedure and can be used as an 'add-on' therapy in patients with reduced ovarian reserve, ovarian failure or implantation failure prior to the in vitro fertilization (IVF) cycle, although it is still regarded as an empirical treatment method. Further studies should be conducted to enlighten the subject.
Key words:  Infertility      IVF      Platelet-rich plasma (PRP)      Ovarian failure     
Submitted:  03 March 2021      Revised:  26 March 2021      Accepted:  29 April 2021      Published:  15 October 2021     
*Corresponding Author(s):  Pelin Kutlu     E-mail:  kutlupelin@gmail.com

Cite this article: 

Pelin Kutlu, Seda Karabulut, Oya Korkmaz. Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1025-1031.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog4805165     OR     https://ceog.imrpress.com/EN/Y2021/V48/I5/1025

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