Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (4): 962-968    DOI: 10.31083/j.ceog4804152
Original Research Previous articles | Next articles
Correlative factors associated with the recurrence of ovarian endometriosis: a retrospective study
Xi-Wa Zhao1, †, Meng-Meng Zhang1, †, Jian Zhao1, Wei Zhao1, Shan Kang1, *()
1Department of Obstetrics and Gynecology, Fourth Hospital, Hebei Medical University, 050011 Shijiazhuang, Hebei, China
Download:  PDF(526KB)  ( 48 ) Full text   ( 8 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Background: The aim of this study was to confirm and analyze the correlative factors that could influence the recurrence of ovarian endometriosis after conservative surgery, including both risk and protective factors. Methods: From January 2010 to January 2018, a retrospective study was conducted which included 1080 patients with ovarian endometriosis who received a minimum of 2 years of follow-up after conservative surgery at a university-based tertiary care hospital. Recurrence was defined as the presence of ovarian cysts larger than 2 cm detected by ultrasonography within 2 years after surgery. The effects of twenty correlative variables on recurrence were evaluated. Results: The cumulative 2-year recurrence rate of ovarian endometriosis after conservative surgery was 15%. According to the logistic regression analysis, the significant risk factors that were independently associated with high recurrence of endometriosis were previous medical treatment of endometriosis (odds ratio [OR] = 2.06; 95% confidence interval [95% CI] = 1.27–3.34; P = 0.004), painful nodules in the pouch of Douglas (OR = 2.44; 95% CI = 1.23–4.85; P = 0.011), largest cyst diameter (OR = 1.54; 95% CI = 1.08–2.18; P = 0.016) and bilateral ovarian involvement (OR = 1.69; 95% CI = 1.19–2.39; P = 0.003). Moreover, the protective factors that were independently associated with low recurrence of endometriosis were postoperative medical treatment (OR = 0.59; 95% CI = 0.42–0.84; P = 0.003) and postoperative pregnancy (OR = 0.34; 95% CI = 0.19–0.62; P < 0.0001). Conclusions: The results of this retrospective analysis of 1080 patients might help predict the prognosis of patients with ovarian endometriosis after conservative surgery and benefit the clinical management of ovarian endometriosis.
Key words:  Ovarian endometriosis      Conservative surgery      Recurrence      Risk factor      Protective factor     
Submitted:  14 March 2021      Revised:  25 April 2021      Accepted:  01 June 2021      Published:  15 August 2021     
*Corresponding Author(s):  ssy19900812@126.com; ksjq62cn@sina.com (Shan Kang)   
About author:  These authors contributed equally.

Cite this article: 

Xi-Wa Zhao, Meng-Meng Zhang, Jian Zhao, Wei Zhao, Shan Kang. Correlative factors associated with the recurrence of ovarian endometriosis: a retrospective study. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(4): 962-968.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog4804152     OR     https://ceog.imrpress.com/EN/Y2021/V48/I4/962

[1] Jian-Sheng Wei, Min-Yan Zhang, Shen Liu, Kang Li, Jun-Jie Fu, Peng Lin. Oophoropexy to prevent adnexal torsion recurrence in children[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1089-1093.
[2] Keiko Nemoto Murofushi, Reiko Tanaka, Ayako Ohkawa, Haruko Numajiri, Toshiyuki Okumura, Hideyuki Sakurai. Outcomes and dose—volume parameters for computed tomography-based brachytherapy planning for vaginal recurrence of uterine cancer primarily treated with surgery[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 601-606.
[3] X.Y. Zhou, K.X. Li, X.M. Shu. Analysis and discussion of high-risk factors in nine cases of uterine scar combined with complete uterine rupture[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 769-773.
[4] J. Ogawa, S. Suzuki. Risk factors of self-interruption of medications for mental disorders in pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 576-578.
[5] Li Li Zhang, Hua Shu, Shuai Zhang, Tian Tian Wang, Lan Lan Zhang. Pregnancy outcomes and risk factors in pregnant women with systemic lupus erythematosus[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 189-193.
[6] T. T. Kitova, B. D. Kitov, E. H. Uchikova, N. T. Ahmad. Maternal age - a risk factor for congenital hydrocephalus[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 257-261.
[7] K.Y. Yun, S.Y. Hwang, H.J. Lee, S.C. Kim, J.K. Joo, D.S. Suh, K.H. Kim, K.S. Lee. The association of body mass index with incidence, stage and recurrence of endometriosis: case-control study in Korean women[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(1): 53-56.
[8] Y.-S. Kim, J.-Y. Hwang, T.-H. Kim, E.-G. Lee, H.-H. Lee. Genome-wide association study of recurrent endometriosis related with ovarian cancer[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 553-559.
[9] S.M.S. Fernandes, J.C.L. Ribalta, N.M.G. Speck, Y. Yamamura. Treatment of uterine cervical ectopy with acupuncture and analysis of risk factors in the metaplastic process[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 601-605.
[10] B. Luo, L. Luo. Simultaneous cornual heterotopic and intrauterine pregnancy following in vitro fertilization/embryo transfer: new conservative surgery with laparoscopic lesion resection[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 482-484.
[11] J. Agah, F. Roodsarabi, A. Manzuri, M. Amirpour, A. Hosseinzadeh. Prevalence and associated risk factors of gestational diabetes mellitus in a tertiary hospital in Iran[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(1): 85-89.
[12] A.A. Rouzi, R. Alamoudi, S. Kafy, L. Ashkar. A case of recurrent posterior reversible encephalopathy syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(1): 143-145.
[13] M. Terzic, J. Dotlic, M. Vasiljevic, S. Andrijasevic, M. Norton, S. Terzic, A. S. Laganà, A. Vereczkey, N. Arsenovic. Endometrial polyps in infertility patients: the first study of their clinical characteristics[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(5): 692-698.
[14] H. Kobayashi, T. Tsunemi, J. Akasaka, N. Koike, A. Shigemitsu. F. Ito, Y. Yamada, E. Fujii. Preeclampsia as a parental epigenetic disease[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 493-502.
[15] M. Li, L. Riming, W. Zhe, W. Hong, H. Xiaofei, C. Lina, Z. Zhengfang, W. Xuebo, W. Ning, S. Chengming, H. Qing-qing, L. Hailiang, W. Hui. Non-invasive prenatal screening for chromosome 21, 18, and 13 aneuploidies in a mixed risk factors pregnancy population[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 523-528.
No Suggested Reading articles found!