Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (4): 787-794    DOI: 10.31083/j.ceog4804126
Special Issue: Updates in obstetrics and gynecology
Review Previous articles | Next articles
Fertility-sparing in cancer patients
Sema Karakaş1, *(), Cihan Kaya2, Sebastian Daniel Schäfer3, Mislav Mikuš4, Milan Terzic5, 6, 7, Bekhzod Abdullaev8, Alessandra Andrisani9
1Department of Gynecological Oncology, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, 34147 Istanbul, Turkey
2Department of Obstetrics and Gynecology, Acibadem Mehmet Ali Aydinlar University, Acibadem Bakirkoy Hospital, 34147 Istanbul, Turkey
3Department of Obstetrics and Gynecology, University of Münster, 48149 Münster, Germany
4Department of Obstetrics and Gynecology, University Hospital Center Zagreb, 10000 Zagreb, Croatia
5Department of Medicine, Nazarbayev University School of Medicine, 020000 Nur-Sultan, Kazakhstan
6Clinical Academic Department of Women's Health, National Research Center of Mother and Child Health, University Medical Center, 020000 Nur-Sultan, Kazakhstan
7Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
8Department of International Relations and Scientific Development, Akfa University, 100190 Tashkent, Uzbekistan
9Department of Women's and Children's Health, University of Padua, 35122 Padua, Italy
Download:  PDF(138KB)  ( 92 ) Full text   ( 11 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Objective: This review aimed to investigate and summarize the current evidence on fertility-sparing options in cancer patients. Mechanism: Fertility preservation methods are becoming popular through the improved prognosis of cancer patients at a younger age and early diagnostic tools. However, currently, more and more women are suffering from iatrogenic ovarian failure and fertility loss because of cancer treatment. Most treatments have been used for hematological malignancies, but different gynecological cancers can be eligible. Findings in brief: Fertility preserving strategies such as oocyte and embryo cryopreservation, ovarian tissue preservation, ovarian transposition, and aspiration of ovarian follicles are the methods that could be suggested to the patients. The current knowledge supports oocyte and embryo cryopreservation as feasible, safe, and effective treatment approaches for cancer patients seeking fertility preservation. Conclusions: Robust evidence is still needed to prove the effectiveness of cryopreservation of the ovarian tissue and ovarian follicle aspiration approaches since these techniques are still in early their steps.
Key words:  Cryopreservation      Infertility      Organ transplants      Ovarian neoplasms     
Submitted:  08 February 2021      Revised:  30 March 2021      Accepted:  31 March 2021      Published:  15 August 2021     
*Corresponding Author(s):  Sema Karakaş     E-mail:  semaakyildiz@hotmail.com

Cite this article: 

Sema Karakaş, Cihan Kaya, Sebastian Daniel Schäfer, Mislav Mikuš, Milan Terzic, Bekhzod Abdullaev, Alessandra Andrisani. Fertility-sparing in cancer patients. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(4): 787-794.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog4804126     OR     https://ceog.imrpress.com/EN/Y2021/V48/I4/787

[1] Pelin Kutlu, Seda Karabulut, Oya Korkmaz. Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1025-1031.
[2] Arzu Yurci, Nur Dokuzeylul Gungor, Tugba Gurbuz. Defective expression of endometrial BMP-2 contributes to subfertility in women with unexplained infertility[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(5): 1094-1098.
[3] Lorenz Hinterleitner, Herbert Kiss, Johannes Ott. The impact of Cesarean section on female fertility: a narrative review[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(4): 781-786.
[4] Martin Klein, Lenka Lapides, Denisa Fecmanová, Ivan Varga. Novel cellular entities and their role in the etiopathogenesis of female idiopathic infertility—a review article[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 461-465.
[5] Banuhan Şahin, Buğra Şahin, Pervin Karlı, Görker Sel, Şafak Hatırnaz, Osman Fadıl Kara, Andrea Tinelli. Level of depression and hopelessness among women with infertility during the outbreak of COVID-19: a cross-sectional investigation[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 594-600.
[6] R. Duraker, E.S. Guvendag Guven, S. Dilbaz, A. Mentese, S. Aydın, S. Guven. Oxidative stress status in severe OHSS patients who underwent long agonist protocol intracytoplasmic sperm injection cycles[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 312-316.
[7] A. Yaylalı, M. Bakacak, Z. Bakacak, F. Tolun. An investigation of the effects on follicular-embryonal development and pregnancy outcomes of serum and follicular fluid ischemia-modified albumin in cases of unexplained infertility receiving in vitro fertilization treatment[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 835-839.
[8] I. Thanaboonyawat, P. Chera-aree, S. Petyim, R. Choavaratana, P. Laokirkkiat. The effect of three-month topical testosterone gel application on semen quality in men with oligozoospermia and low serum testosterone levels[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 875-881.
[9] K. Okuno, K. Kitaya, N. Kim, K. Yamaguchi, H. Matsubayashi, T. Ishikawa. Case report of successful live birth in an infertile couple with male idiopathic hypogonadotropic hypogonadism/azoospermia and atypical polypoid adenomyoma of the uterus[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 972-973.
[10] B.G. Kadioglu, B. Gundogdu, N. Kurt, A. Ozbek Bilgin, H. Suleyman, Z. Suleyman. The effect of rhodiola rosea root extract on stress-induced ovarian damage, infertility and reproductive disorders in female rats[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 530-536.
[11] J.H. Check, D.L. Check, M.P. Dougherty, G. DiAntonio. Purposeful cryopreservation of sperm prior to intrauterine insemination to overcome the embryo implantation defect associated with sperm with a subnormal hypoosmotic swelling test[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 432-433.
[12] S. J. Knight, A. D. Smith, H. Kim, A. C. Collier. Human placental suppressors of cytokine signalling (SOCS) and inflammatory cytokines are dysregulated in assisted reproduction, advanced maternal age and pre-term birth[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 277-286.
[13] S.Y. Jung, H.Y. Cho, S.H. Lee, S. Lim, K.B. Lee. Pregnancy outcomes of a giant primary ovarian leiomyoma in the first trimester[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(1): 135-138.
[14] Hue HJ, Kim SK, Choi JY, Suh DH, Kim KD, No JH, Lee JR, Jee BC, Kim YB, Jeon HW. Previous ovarian surgery increases the risk of tubal factor infertility[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(1): 84-88.
[15] M. Minase, T. Miyamoto, N. Hayashi, G. Minase, K. Nishiwaki, K. Sengoku. A patient with a didelphys vaginal septum and infertility diagnosed by laparoscopy and magnetic resonance imaging[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 988-989.
No Suggested Reading articles found!