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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (3): 550-554    DOI: 10.31083/j.ceog.2021.03.2348
Original Research Previous articles | Next articles
A dilemma for women: having many children risks deterioration of diastolic functions
Mehmet Ozgeyik1, *(), Ozge Turgay Yildirim1, Mevlut Serdar Kuyumcu2, Mehmet Ali Astarcioglu3
1Department of Cardiology, Eskisehir City Hospital, 26100 Eskisehir, Turkey
2Department of Cardiology, Faculty of Medicine, Suleyman Demirel University, 32000 Isparta, Turkey
3Department of Cardiology, Faculty of Medicine, Kutahya Dumlupinar University, 43000 Kutahya, Turkey
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Abstract  
Background: Echocardiography is the most widely used diagnostic tool for detecting changes in cardiac function. Pregnancy is a dynamic process that affects the cardiovascular system and recent studies have shown that increased parity may cause irreversible changes in the cardiovascular system. In this study, we aimed to evaluate echocardiographic changes in women, especially grand multiparous (6 to 9 parities) and great grand multiparous (more than 9 parities) women, after all their pregnancies had finished. Methods: This was a cross-sectional study and contained 195 female patients. Women with one delivery were defined as primiparous (PP), 2 to 5 deliveries were defined as multiparous (MP), 6 to 9 deliveries were defined as grand multiparous (GMP) and more than 9 deliveries were defined as great grand multiparous (GGMP). Results: The mean age at cardiac evaluation was 50.6 ± 16.3 and mean parity was 6.5 ± 4.2. Diastolic dysfunction was grouped as grade 1–3 and this was determined according to the E/e' ratio. Spearman correlation analysis showed that diastolic dysfunction had positive correlations with parity, age, hypertension, and diabetes mellitus. Receiver-operating curve (ROC) analysis showed that the best cut-off value of the parity number for predicting left ventricular diastolic dysfunction was 6.5, with 66.3% sensitivity and 66.7% specificity. Discussion: In the present study, we showed that diastolic dysfunction significantly increased as the number of pregnancies increased. Additionally, the cut-off value of parity for diastolic dysfunction was 6.5 which is higher than other studies.
Key words:  Pregnancy      Echocardiography      Left ventricular dysfunction     
Submitted:  04 November 2020      Revised:  10 December 2020      Accepted:  11 December 2020      Published:  15 June 2021     
*Corresponding Author(s):  Mehmet Ozgeyik     E-mail:  mehmetozgeyik@hotmail.com

Cite this article: 

Mehmet Ozgeyik, Ozge Turgay Yildirim, Mevlut Serdar Kuyumcu, Mehmet Ali Astarcioglu. A dilemma for women: having many children risks deterioration of diastolic functions. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(3): 550-554.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.03.2348     OR     https://ceog.imrpress.com/EN/Y2021/V48/I3/550

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