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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (2): 323-330    DOI: 10.31083/j.ceog.2021.02.2329
Original Research Previous articles | Next articles
Clinical factors associated with anxiety and depression in Korean women with abnormal uterine bleeding
Hae Nam Lee1, Hui Ryeon Ju1, Ji Min Seo1, Gi Soo Um1, Min Jeong Kim1, *()
1Department of Obstetrics and Gynecology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 14647 Seoul, Republic of Korea
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Abstract  
The aims of the study were to investigate the prevalence of anxiety and depression and to correlate symptoms of anxiety and depression with abnormal uterine bleeding (AUB) in Korean women. Our study included 124 Korean premenopausal women aged 15–55 without treatment of psychiatric disorders, who visited one university hospital due to AUB between September 2015 and December 2019. The Korean Beck Anxiety Inventory (K-BAI) and the Korean Beck Depression-II (K-BDI-II) were used to assess Anxiety and depression symptoms. We also analyzed obstetrical and clinical data to assess the association between anxiety and depression with AUB. The cut-off scores for possible anxiety disorder were met by 37.9% (47 women) of the patients and for possible depression disorder by 19.5% (24 women). The most common menstrual associated symptoms were heavy menstrual bleeding (80.6%), dysmenorrhea (55.6%), and irregular menstrual cycles (33.9%). More women with AUB in our study had anxiety as measured by the K-BAI and depression as measured by the K-BDI-II than general Korean population. A history of abortion and cesarean section (C/sec) were related with anxiety, whereas a history of minor surgery was related to depression. Anxiety and depression (r = 0.629, P < 0.001) were correlated with AUB. According to age, variable factors affect anxiety (history of abortion, history of C/sec, minor surgery, Body mass index [BMI], history of OCs) and depression (BMI ≥ 25, history of minor surgery). We have found that anxiety and depression seem to be underestimated in Korean women with AUB symptoms. The relationship between the development of anxiety and depression with variable factors are unknown and therefore, further study is needed to clarify and understand the effects of AUB. To improve the health of women with AUB, screening for mental health issues is needed for early detection and treatment of anxiety and depression.
Key words:  Abnormal uterine bleeding      Heavy menstrual bleeding      Anxiety      Depression     
Submitted:  18 October 2020      Revised:  04 January 2021      Accepted:  25 January 2021      Published:  15 April 2021     
Fund: 
Institute of Clinical Medicine Research of Bucheon St. Mary's Hospital, Research Fund, 2020
HC14C1062/Korea Health Technology R&D Project through the Korean Health Industry Development Institute (KHIDI)
*Corresponding Author(s):  Min Jeong Kim     E-mail:  poouh74@catholic.ac.kr

Cite this article: 

Hae Nam Lee, Hui Ryeon Ju, Ji Min Seo, Gi Soo Um, Min Jeong Kim. Clinical factors associated with anxiety and depression in Korean women with abnormal uterine bleeding. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 323-330.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.02.2329     OR     https://ceog.imrpress.com/EN/Y2021/V48/I2/323

[1] Hazem Al-Mandeel. Should diagnostic hysteroscopy be performed routinely following thermal balloon endometrial ablation? A case report of thermal bowel injury and literature review[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 423-425.
[2] L.L. Xu, J.Q. Li, Y.Q. Pu, C. Zhou, S.W. Feng, Q. Luo. Effect of prenatal depression during late pregnancy on maternal and neonatal outcomes[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 681-686.
[3] Y. Akdemir, M. Karadeniz. A psychological factor associated with pain during intrauterine device insertion: emotional reactivity[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 335-340.
[4] G. Keren, G. Ayala. Factors associated with hyperemesis gravidarum[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 391-395.
[5] J.D. Jaremek, D.R. Chinniah, A. Słopień, P. Rynio, R. Słopień. Menopausal depression - state of art[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 859-861.
[6] H. Aydoğmuş, S. Gençdal, Z. Kolsuz, F. Elmalı, S. Aydoğmuş, S. Kelekçi. Is there a relationship between systemic inflammatory markers and abnormal uterine bleeding in unclassifiable cases according to the PALM-COEIN system?[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 752-756.
[7] A. Średniawa, K. Kruk, D. Ł. Jarczewska, K. Żabicka, M. Golonka, R. Krępa, T. Tomasik. Postpartum depression and breastfeeding in primary care in Krakow, Poland[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(6): 880-885.
[8] K. Bakay, H. Ulubaşoğlu, T. Atan, H. Alaçam, D. Güven, S. Batioğlu. The effect of physical activity on the levels of the hormones, serotonin and melatonin in premenstrual syndrome[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(3): 425-427.
[9] E. Djakovic, S. Rakic. Depression, anxiety, and stress after preterm delivery: role of previous progesterone therapy[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(2): 214-217.
[10] A.M. Eman, M.E. Mahmoud. Effect of aerobic exercises versus foot reflexology on post-menopausal depression[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(5): 726-729.
[11] J.H. Check, A. Jaffe. Dextroamphetamine sulfate provided quick relief of severe post-partum depression that was recalcitrant to standard antidepressants and psychotherapy[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 272-274.
[12] F. Chen, H. Duan, Y. Zhang, Y. Liu, X. Wang, Y. Guo. A giant nabothian cyst with massive abnormal uterine bleeding: a case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(2): 326-328.
[1] Eli M. Roth, Michael H. Davidson. PCSK9 Inhibitors: Mechanism of Action, Efficacy, and Safety[J]. Reviews in Cardiovascular Medicine, 2018, 19(S1): 31 -46 .
[2] Sandeep K. Krishnan, Norman E. Lepor. Acute and Chronic Cardiovascular Effects of Hyperkalemia: New Insights Into Prevention and Clinical Management[J]. Reviews in Cardiovascular Medicine, 2016, 17(S1): 9 -21 .
[3] Prakash C. Deedwania. Management of Patients With Stable Angina and Type 2 Diabetes[J]. Reviews in Cardiovascular Medicine, 2015, 16(2): 105 -113 .
[4] Peter Shalit. Management of Dyslipidemia in Patients With Human Immunodeficiency Virus[J]. Reviews in Cardiovascular Medicine, 2014, 15(S1): 38 -46 .
[5] Sophie Mavrogeni, Fabrizio Cantini, Gerald M. Pohost. Systemic Vasculitis: An Underestimated Cause of Heart Failure—Assessment by Cardiovascular Magnetic Resonance[J]. Reviews in Cardiovascular Medicine, 2013, 14(1): 49 -55 .
[6] Prabhjot Singh Nijjar, Anoop Parameswaran, Aman M. Amanullah. Evaluation of Anomalous Aortic Origins of the Coronaries by 64-Slice Cardiac Computed Tomography[J]. Reviews in Cardiovascular Medicine, 2007, 8(3): 175 -181 .
[7] Jeffrey W. Moses, Stephane Carlier, Issam Moussa. Lesion Preparation Prior to Stenting[J]. Reviews in Cardiovascular Medicine, 2004, 5(S2): 16 -21 .
[8] Dean J. Kereiakes. Coronary Small-Vessel Stenting in the Era of Drug Elution[J]. Reviews in Cardiovascular Medicine, 2004, 5(S2): 34 -45 .
[9] M. Pakiž, L. Lukman, N. Kozar. Patients' and physicians' expectations differ significantly during the follow-up period after completion of primary treatment of gynecological or breast cancer[J]. European Journal of Gynaecological Oncology, 2019, 40(5): 781 -786 .
[10] T. Tomimatsu, S. Mabuchi, T. Tsuboyama, Y. Hori, S. Sekine, T. Kimura. Malignant transformation of uterine leiomyoma: suggested by clinical, imaging, histological, and genetic findings[J]. European Journal of Gynaecological Oncology, 2019, 40(5): 879 -882 .