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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (2): 439-443    DOI: 10.31083/j.ceog.2021.02.2194
Case Report Previous articles | Next articles
Prenatal sonographic findings and management of placental mesenchymal dysplasia
Suchaya Luewan1, Pakorn Chaksuwat1, Tip Pongsuvareeyakul2, Theera Tongsong1, *()
1Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, Thailand
2Department of Pathology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, Thailand
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Abstract  
Placental mesenchymal dysplasia (PMD) is a rare disorder of the placenta characterized by placentomegaly with diffuse hydropic stem villous, aneurysmally dilated vessels, and lack of trophoblastic proliferation. Case: The prenatal ultrasound of a 34-year-old woman (G1P0) at 33 weeks of gestation showed an enlarged placenta with multiple cystic lesions, heterogeneous echoes with no active blood flow, and fetal growth restriction (FGR). The differential diagnosis involved partial mole, placental hemorrhage, and PMD. She developed preeclampsia at 38 weeks of gestation and gave birth to a normally formed, growth-restricted baby. The placenta, weighing 785 g, showed scattered cystic vesicles in the parenchyma. The histology shows enlarged edematous stem villi with occasional cistern formation and no area of chorioangioma or features of molar pregnancy. PMD associated fetal growth restriction was diagnosed. Conclusion: PMD has prenatal ultrasound result resembling those of partial mole, placental hemorrhage and chorioangioma, but the fetus is phenotypically normal. Nevertheless, fetal surveillance is essential.
Key words:  Placental mesenchymal dysplasia      Prenatal diagnosis      Ultrasound     
Submitted:  20 June 2020      Revised:  22 August 2020      Accepted:  31 August 2020      Published:  15 April 2021     
Fund: 
CMU-2563/Chiang Mai University Research Fund
*Corresponding Author(s):  Theera Tongsong     E-mail:  theera.t@cmu.ac.th

Cite this article: 

Suchaya Luewan, Pakorn Chaksuwat, Tip Pongsuvareeyakul, Theera Tongsong. Prenatal sonographic findings and management of placental mesenchymal dysplasia. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(2): 439-443.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.02.2194     OR     https://ceog.imrpress.com/EN/Y2021/V48/I2/439

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[2] Sandeep K. Krishnan, Norman E. Lepor. Acute and Chronic Cardiovascular Effects of Hyperkalemia: New Insights Into Prevention and Clinical Management[J]. Reviews in Cardiovascular Medicine, 2016, 17(S1): 9 -21 .
[3] Ibrahim Sidiqi, Patrick Alexander. Current Advances in Endovascular Therapy for Infrapopliteal Artery Disease[J]. Reviews in Cardiovascular Medicine, 2015, 16(1): 36 -50 .
[4] Prakash C. Deedwania. Management of Patients With Stable Angina and Type 2 Diabetes[J]. Reviews in Cardiovascular Medicine, 2015, 16(2): 105 -113 .
[5] Peter Shalit. Management of Dyslipidemia in Patients With Human Immunodeficiency Virus[J]. Reviews in Cardiovascular Medicine, 2014, 15(S1): 38 -46 .
[6] Sophie Mavrogeni, Fabrizio Cantini, Gerald M. Pohost. Systemic Vasculitis: An Underestimated Cause of Heart Failure—Assessment by Cardiovascular Magnetic Resonance[J]. Reviews in Cardiovascular Medicine, 2013, 14(1): 49 -55 .
[7] George L. Smith. Appropriate Use Criteria: The Gold Standard, or a Mechanism for the Derogation of Clinical Judgment?[J]. Reviews in Cardiovascular Medicine, 2011, 12(2): 105 .
[8] Jeffrey W. Moses, Stephane Carlier, Issam Moussa. Lesion Preparation Prior to Stenting[J]. Reviews in Cardiovascular Medicine, 2004, 5(S2): 16 -21 .
[9] Dean J. Kereiakes. Coronary Small-Vessel Stenting in the Era of Drug Elution[J]. Reviews in Cardiovascular Medicine, 2004, 5(S2): 34 -45 .
[10] M. Pakiž, L. Lukman, N. Kozar. Patients' and physicians' expectations differ significantly during the follow-up period after completion of primary treatment of gynecological or breast cancer[J]. European Journal of Gynaecological Oncology, 2019, 40(5): 781 -786 .