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Clinical and Experimental Obstetrics & Gynecology  2021, Vol. 48 Issue (1): 59-65    DOI: 10.31083/j.ceog.2021.01.2104
Original Research Previous articles | Next articles
Uterine artery embolization using gelatin sponge particles for symptomatic focal and diffuse adenomyosis
Ja Young Kim1, Yun Gyu Song1, *(), Chang-Woon Kim2, Moon Ok Lee3
1Department of Radiology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, 51353 Changwon, Korea
2Department of Obstetrics and Gynecology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, 51353 Changwon, Korea
3Department of Anesthesia and Pain Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, 51353 Changwon, Korea
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Abstract  
Objective: To evaluate the effectiveness of uterine artery embolization (UAE) with gelatin sponge particles for symptomatic focal and diffuse adenomyosis. Materials and Methods: This was a retrospective study conducted between January 2014 and December 2019. All women underwent UAE for symptomatic adenomyosis without leiomyomas. Gelatin sponge particles were used in all cases. Patients were assessed for effectiveness of symptom control, changes in uterine volume, and degree of tumor necrosis on magnetic resonance (MR) imaging. Results: One hundred and sixty-three patients underwent UAE. There were statistically significant differences in bleeding score, pain score, and uterine volume at three months after UAE (P < 0.001, P < 0.001, and P < 0.001, respectively). Complete tumor necrosis occurred in 66.9% of casesafter UAE. Proportion of complete necrosis were significantly different in cases with focal adenomyosis compared with diffuse adenomyosis (P = 0.023). Symptom recurrence occurred in 20.6% of cases at 12-month follow-up. Focal adenomyosis patients with complete necrosis had no recurrent menorrhagia and dysmenorrhea. No major complications were observed. Conclusions: UAE using gelatin sponge particles is an effective and safe treatment for symptomatic adenomyosis. Patients with focal adenomyosis with complete necrosis after UAE had no symptom recurrence at midterm follow-up.
Key words:  Uterine artery embolization (UAE)      Adenomyosis      Gelatin sponge particles     
Submitted:  06 April 2020      Revised:  02 July 2020      Accepted:  14 July 2020      Published:  15 February 2021     
*Corresponding Author(s):  Yun Gyu Song     E-mail:  yawoo114@naver.com

Cite this article: 

Ja Young Kim, Yun Gyu Song, Chang-Woon Kim, Moon Ok Lee. Uterine artery embolization using gelatin sponge particles for symptomatic focal and diffuse adenomyosis. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 59-65.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2021.01.2104     OR     https://ceog.imrpress.com/EN/Y2021/V48/I1/59

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