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Clinical and Experimental Obstetrics & Gynecology  2020, Vol. 47 Issue (6): 867-874    DOI: 10.31083/j.ceog.2020.06.5516
Original Research Previous articles | Next articles
Elective embryo or fetal reduction for caesarean scar pregnancy combined with intrauterine pregnancy
J.R. Huang1, X. Li1, Q.Z. Peng1, J.J. Zhang1, X.X. Lin1, L.Q. Xie1, X.H. Wu1, W.S. Zhang1, 2, *()
1Department of Obstetrics, Xiangya Hospital Central South University, Changsha, Hunan, P.R. China
2Hunan Engineering Research Center of Early Life Development and Disease Prevention, Changsha, Hunan, P.R. China
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Abstract  
Objective: The purpose of this study is to report and discuss the use of elective embryo reduction to treat a cesarean scar pregnancy (CSP) combined with intrauterine pregnancy after assisted reproduction, and its clinical outcomes. Material and Methods: Clinical data from six patients who were diagnosed with CSP combined with intrauterine pregnancy were retrospectively collected and analyzed. Four patients underwent elective embryo or fetal reduction following local injection of potassium chloride (reduction group), while the other two patients chose to continue their multiple pregnancies (observation group). Results: All patients were pregnant with multiple chorionic and amniotic fetuses after assisted reproduction. Mild placenta accreta was observed in one patient in the reduction group. In this group, hemorrhage volume during delivery was from 400 to 900 mL, and the average birth weight was 2,776 g. Placenta accreta spectrum occurred in both patients in the observation group, and they gave birth prematurely between 32 and 34 weeks. Conclusion: CSP combined with intrauterine pregnancy was treated using elective embryo or fetal reduction, which may improve maternal and fetal safety. Content: Outcomes of cesarean scar pregnancy with intrauterine pregnancy with or without elective embryo reduction.
Key words:  Heterotopic cesarean scar pregnancy      Multifetal pregnancies      Pregnancy reduction     
Submitted:  21 January 2020      Accepted:  17 June 2020      Published:  15 December 2020     
Fund: 
CX2017B067/ the Hunan Provincial Innovation Foundation for Postgraduate
2014BAI05B05/ the National Twelfth-Five Year Research and Development Program of China
2017SK2151, 2017SK1033/ the Science and Technology Project of Hunan Province
81974236, 81903696, 81571516/ the National Natural Science Foundation of China
2016YFC1000206/ the National Key Research and Development Program of China
2019SK1010/ the Major Scientific and Technological Projects for Collaborative Prevention and Control of Birth Defects in Hunan Province
*Corresponding Author(s):  WEISHE ZHANG     E-mail:  zhangweishe@yeah.net

Cite this article: 

J.R. Huang, X. Li, Q.Z. Peng, J.J. Zhang, X.X. Lin, L.Q. Xie, X.H. Wu, W.S. Zhang. Elective embryo or fetal reduction for caesarean scar pregnancy combined with intrauterine pregnancy. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 867-874.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2020.06.5516     OR     https://ceog.imrpress.com/EN/Y2020/V47/I6/867

[1] Jing-Jing Jiang, Ting Han, Yan-Hui Zhu. The early second-trimester multifetal pregnancy reduction improves pregnancy outcome[J]. Clinical and Experimental Obstetrics & Gynecology, 2021, 48(1): 164-167.
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