Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2020, Vol. 47 Issue (5): 681-686    DOI: 10.31083/j.ceog.2020.05.5398
Original Research Previous articles | Next articles
Effect of prenatal depression during late pregnancy on maternal and neonatal outcomes
L.L. Xu1, J.Q. Li1, Y.Q. Pu1, C. Zhou2, S.W. Feng1, *(), Q. Luo1, *()
1Department of Obstetrics, Women’s Hospital, School of Medicine, Zhejiang University, Zhejiang, P.R. China
2Medical School, Hangzhou Normal University, Zhejiang, P.R. China
Download:  PDF(263KB)  ( 135 ) Full text   ( 22 )
Export:  BibTeX | EndNote (RIS)      
Abstract  
Aim: To determine whether prenatal depression during late pregnancy affect maternal and neonatal outcomes. Methods: The clinical data of 595 pregnant patients in our hospital during January 2016 to December 2017 were studied. These participants were assigned into three groups as mild-to-moderate depression group, severe depression group and non-depression group according to the Edinburgh postnatal depressive scale (EPDS). Results: Compared with the women without depression or with mild-to-moderate depression, pregnant patients with severe depression were likely to suffer from preterm birth (p < 0.05). There was no association between the mild-to-moderate depression, severe depression group and the non-depression group about neonatal outcomes (all p > 0.05). Conclusion: Severe prenatal depression during late pregnancy is significantly associated with increased risk of preterm birth, while mild-to-moderate prenatal depression would not affect maternal and neonatal outcomes.
Key words:  Prenatal depression      Late pregnancy      Preterm birth     
Submitted:  08 September 2019      Accepted:  27 May 2020      Published:  15 October 2020     
Fund: 
81571447/National Natural Science Foundation of China
2018C03010/Key Research Project of Zhejiang Province
2018RC005/Construction of Medical Core Subjects and Innovation Platform in Zhejiang Province Grant
*Corresponding Author(s):  fengsw@zju.edu.cn (SUWEN FENG); luoq@zju.edu.cn (QIONG LUO)   

Cite this article: 

L.L. Xu, J.Q. Li, Y.Q. Pu, C. Zhou, S.W. Feng, Q. Luo. Effect of prenatal depression during late pregnancy on maternal and neonatal outcomes. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 681-686.

URL: 

https://ceog.imrpress.com/EN/10.31083/j.ceog.2020.05.5398     OR     https://ceog.imrpress.com/EN/Y2020/V47/I5/681

[1] N. Al-Husban, A. Hababeh, M. Al-Kasasbeh, R. Odeh, M. Shaheen, D. Moughrabi, D. Zabalawi. Thyroid stimulating hormone (TSH) level variations in early pregnancy and feto-maternal outcome; retrospective study[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 675-680.
[2] F. Wang, Z.X. Liang, W.R. Mao, S.N. He, D.Q. Chen. Influence of pre-pregnancy body mass index and gestational weight gain in twin pregnancies on blood glucose, serum lipid and perinatal outcomes[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 376-382.
[3] A. Kalok, N.H.A. Aziz, D.A. Malik, S.A. Shah, D.N. Nasuruddin, M.H. Omar, N.A.M. Ismail, M.N. Shafiee. Maternal serum vitamin D and spontaneous preterm birth[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(1): 16-20.
[4] S. Borna, B. Teimoori, A. Esmailzadeh, M. Shariat, E. Lesha. Association of cervical length and uterine artery Doppler with threatened preterm labor[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 748-751.
[5] M. Collict, Y. Mucat Baron, M. Gatt, N. Calleja. Advanced maternal age and neonatal outcomes in Malta[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 265-269.
[6] Qingyan Cao, Jing Zhang, Li Zhang, Daijuan Chen, Bing Peng. Decreased levels of UBE2Q1 and CHIP in the placentas of infection related preterm birth[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(5): 762-766.
[7] Ning Hui, Xiuli Li, Shujuan Wang, Yuanguang Meng, Yuan Gao. A third-trimester rupture in a scarred uterus: a case report[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(3): 452-455.
[1] Miao Xie, Geng Zhang, Wei Yin, Xin-Xin Hei, Tao Liu. Cognitive enhancing and antioxidant effects of tetrahydroxystilbene glucoside in Aβ1-42-induced neurodegeneration in mice[J]. Journal of Integrative Neuroscience, 2018, 17(3): 203 -210 .
[2] Andrey F. Iznak, Ekaterina V. Iznak, Tatiana P. Klyushnik, Georgy M. Kobel'kov, Elena V. Damjanovich, Igor V. Oleichik, Lilia I. Abramova. Neurobiological parameters in quantitative prediction of treatment outcome in schizophrenic patients[J]. Journal of Integrative Neuroscience, 2018, 17(3): 221 -228 .
[3] J. Meléndez-Gallardo, A. Eblen-Zajjur. Thermo-dependence of noxious mechanical heterotopic stimulation-dependent modulation of the spinal dorsal horn response to somatosensory stimulation[J]. Journal of Integrative Neuroscience, 2018, 17(3): 249 -256 .
[4] Gerardo Fernández, Nora P. Rotstein, Luis E. Politi, Liliana Castro, Osvaldo Agamennoni. Microsaccadic behavior when developing a complex dynamical activity[J]. Journal of Integrative Neuroscience, 2018, 17(3): 287 -290 .
[5] Alexander Fedotchev, Grigoriy Radchenko, Anna Zemlianaia. Music of the brain approach to health protection[J]. Journal of Integrative Neuroscience, 2018, 17(3): 291 -296 .
[6] Abolfazl Alipour, Sahar Seifzadeh, Hadi Aligholi, Mohammad Nami. QEEG-based neural correlates of decision making in a well-trained eight year-old chess player[J]. Journal of Integrative Neuroscience, 2018, 17(3): 297 -306 .
[7] Lei Guo, Hongyi Shi, Yunge Chen, Hongli Yu. Anti-interference ability of deep spiking neural network[J]. Journal of Integrative Neuroscience, 2018, 17(4): 307 -311 .
[8] Jing Wang, Xiangyi Kong, Lele Cong, Zhongxin Xu, Jianshi Du, Xianling Cong, Hongyan Sun, Yanan Xu, Qing Zhao. Associations between CD33 rs3865444 and ABCA7 rs3764650 polymorphisms and susceptibility to Alzheimer's disease[J]. Journal of Integrative Neuroscience, 2018, 17(4): 313 -321 .
[9] D. I. Stephanova, A. Kossev. Theoretical predication of temperature effects at 20 ℃-42  on adaptive processes in simulated amyotrophic lateral sclerosis[J]. Journal of Integrative Neuroscience, 2018, 17(4): 355 -363 .
[10] Xinqiang Ni, Yingzhao Liao, Limin Li, Xiaoli Zhang, Zhengzhi Wu. Therapeutic role of long non-coding RNA TCONS_00019174 in depressive disorders is dependent on Wnt/$\beta$-catenin signaling pathway[J]. Journal of Integrative Neuroscience, 2018, 17(2): 125 -132 .