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Clinical and Experimental Obstetrics & Gynecology  2020, Vol. 47 Issue (5): 632-637    DOI: 10.31083/j.ceog.2020.05.2223
Systematic Review Previous articles | Next articles
A systematic review and meta-analysis of the reported symptoms of Covid 19 in pregnancy
H.S.O. Abduljabbar1, *(), H. Abduljabar2
1Department of Obstetrics &Gynecology, Medical College, King Abdulaziz University, P.O. Box 80215 Jeddah 21452, Kingdom of Saudi Arabia
2Department of Obstetrics &Gynecology, and Head of IVF Unit at King Faisal Specialties Hospital, Jeddah, Kingdom of Saudi Arabia
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Introduction: The percentage of Symptomatic pregnant and non-pregnant women infected with Covid 19 is the same. The common symptoms in pregnant women are cough, fever, sore throat and myalgia. The objective of this is systematic review and meta-analysis of the commonly reported symptoms of COVID 19 in pregnancy and to compare it to non-pregnant. Methods: Study Design; Systematic review and meta-analysis of published retrospective studies. Searches conducted from December 2019 - April 2020 on PubMed. Medline, EMBASE, ISI Web of Science Electronic database used to collect data, corresponding to the (PRISMA) Preferred Reporting Items for Systematic Meta-Analysis, using the following search terms: keywords "coronavirus, COVID-19, pregnancy". Results: Figure 1 presents the study flow diagram. We identify 114 records through database searching, sixteen further studies recognized through other sources, and 98 papers isolated after duplicates, leaving 32 reports. After screening for titles and abstracts, we found only 27 reports to be potentially suitable and rescued these reports in full text. We excluded seven studies; 20 did not report symptoms of groups of interest. In the process of Screening, 16 were screened. Ten of full-text articles assessed for appropriateness, six full-text articles omitted with reasons, and only Four studies [12-15] were included in the review. Conclusion: The only symptoms that are more common in pregnant than non-pregnant are the sore throat. That concluded that when pregnant women start to have sore throat care should be taken to exclude COVID-19 infection.

Key words:  Coronavirus      COVID-19      Pregnancy     
Submitted:  15 July 2020      Accepted:  24 August 2020      Published:  15 October 2020     
*Corresponding Author(s):  H.S.O. Abduljabbar     E-mail:

Cite this article: 

H.S.O. Abduljabbar, H. Abduljabar. A systematic review and meta-analysis of the reported symptoms of Covid 19 in pregnancy. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 632-637.

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Table 1  — Characteristics of involved studies (PICO).
Author Journal Year Design Population/Wt
Yan J Am J Obs Gyne 23/4/2020 A retrospective review 116/63.4
Breslin N Am J Obs Gyne MFM. 19/4/2020 A retrospective review 43/23.5
Liu D Am J Roentgenol. 18/3/2020 A retrospective review 15/8.2
Huijun Chen The Lancet 12/2/2020 A retrospective review 9/4.9
Total 183/100
(Control) Tian S J Infect. 27/2/2020 A retrospective review 262
Table 2  — Common Symptoms Included Studies (PICO).
Four Common Reported Symptoms
Author Fever Cough Myalgia Sore throat
Yan J 59/116 33/116 15/116 10/116
Breslin N 37/43 14/43 5/43 4/43
Liu D 13/15. 9/15 3/15 2/15
Huijun Chen 7/9 4/9 2/9 1/9
Tian S 215/262 120/262 68/282 18/262
Figure 1.  — Presents the literature search. (Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement) (PRISMA).

Figure 2.  — Forest plot for the four studies.

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