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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (2): 206-210    DOI: 10.12891/ceog4893.2019
Original Research Previous articles | Next articles
Carbon dioxide laser as a new valid treatment of lichen sclerosus
M. C. Teodoro1, G. Scibilia1, E. Lomeo1, B. Pecorino1, *(), A. Galia2, P. Scollo1
1Operative Unit of Obstetrics and Gynecology, Cannizzaro Hospital, Catania, Italy
2Pathology Unit, Cannizzaro Hospital, Catania, Italy
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Purpose of Investigation: To investigate the role of CO2 laser in the patients affected by lichen sclerosus (LS), analyzing histological changes and relief of feminine discomfort. Materials and Methods: The authors report a case series of ten patients with histologically verified LS, undergoing fractional CO2 laser, from January 2017 to December 2017. The mean age of the participants was 55 (range 40-68) years, and five had been previously treated with the topical corticosteroid clobetasol propionate 0.05% ointment with limited efficacy. The overall sessions varied depending on the lichen extension, from one to three treatments. Results: All the patients tolerated the procedure well with re-epithelialization occurring within 3-4 weeks in all cases. Carbon dioxide laser was successful in achieving remarkable symptoms reduction or remission. There was an improvement in the appearance of the introitus, and in elastic opening and closing. Post-treatment histology revealed trophic epithelium with mild acanthosis and small areas with superficial hyperkeratosis. These results were maintained throughout the three-month post-treatment follow-up period. Conclusion: Laser treatment is relatively simple and effective. The histological changes observed in these patients suggest a more comprehensive healing effect of the fractional CO2 laser, not only symptomatic approach. The authors await the next follow-up to establish the duration of the effects. Content: CO2 laser is a valid treatment option for LS, improving discomfort through histological changes of tissue.

Key words:  Laser CO2      Lichen sclerosus      Itch      Dyspareunia      Vulva     
Published:  10 April 2019     
*Corresponding Author(s):  B. PECORINO     E-mail:

Cite this article: 

M. C. Teodoro, G. Scibilia, E. Lomeo, B. Pecorino, A. Galia, P. Scollo. Carbon dioxide laser as a new valid treatment of lichen sclerosus. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 206-210.

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