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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (5): 833-835    DOI: 10.12891/ceog4876.2019
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Effects of tadalafil on the uterine artery of fetal growth restriction
S. Magawa1, *(), H. Tanaka1, S. Maki1, M. Nii1, T. Umekawa1, T. Ikeda1
1Department of Obstetrics and Gynecology, Mie University Faculty Medicine, Mie, Japan
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Abstract  

Fetal growth restriction (FGR) is the most important cause of perinatal morbidity and mortality during the perinatal period. However, there is no established standard regarding the appropriate delivery time or treatment methods for fetuses with FGR. Reduced uterine arterial blood flow has been reported with FGR; however, if this is improved, then FGR may also be improved. Phosphodiesterase 5 inhibitors have vasodilating actions. When administered to the mother, they may improve FGR by improving fetal placental blood flow through improvements in uterine arterial blood flow.
Key words:  Uterine artery bold flow      Fetal growth restriction      PDE5 inhibitor      Tadalafil      Fetus     
Published:  10 October 2019     
*Corresponding Author(s):  S. MAGAWA     E-mail:  shoichimagawa@yahoo.co.jp
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S. Magawa, H. Tanaka, S. Maki, M. Nii, T. Umekawa, T. Ikeda. Effects of tadalafil on the uterine artery of fetal growth restriction. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 833-835.

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https://ceog.imrpress.com/EN/10.12891/ceog4876.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I5/833

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