Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (3): 437-442    DOI: 10.12891/ceog4676.2019
Original Research Previous articles | Next articles
Plasma urotensin-2 as a marker for menstrual irregularities in women: a clinical study
D. Cetin1, *(), M. Yayla1, Y. Baykus2, R. Deniz2
1Department of Pharmacology; Kafkas University Faculty of Medicine, Kars, Turkey
2Department of Gynecology & Obstetrics; Kafkas University Faculty of Medicine, Kars, Turkey
Download:  PDF(537KB)  ( 192 ) Full text   ( 4 )
Export:  BibTeX | EndNote (RIS)      
Abstract  

Purpose of Investigation: The objectives of this study were to evaluate urotensin 2 (UT-2) serum levels, a potent vasoconstrictor, in women with irregular menstrual irregularities and to determine its course in irregular menstrual cycles for the first time in the literature. It aims to determine the possible physiological roles of UT-2 by comparing the hormonal changes occurring in women with menstrual irregularities and their UT-2 levels. Materials and Methods: In this study, 120 patients with irregular menstruation was collected on day 3 of the menstrual cycle. Patients were divided into four groups: oligomenorrhea, hypomenorrhea, polymenorrhea, and menorrhagia/ menometrorrhagia. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), prolactin (PRL), and UT-2 levels were measured in serum. Results: Serum FSH, LH, and TSH levels were not significantly different between the groups. In this study a correlation test between UT-2 and PRL levels was carried out. This resulted in a statistically inverse correlation between increased UT-2 and decreased PRL levels among the groups being shown. Conclusion: It is interesting to note that the levels of urotensin in this study were higher in women with menstrual irregularities than in healthy individuals and that serum PRL levels in women with menstrual irregularities were lower than those in the control group, while still remaining within normal range.

Key words:  Menstruation      Irregularity      Women      Urotensin 2      Prolactin     
Published:  10 June 2019     
*Corresponding Author(s):  D. CETIN     E-mail:  damlacetin.erz@gmail.com

Cite this article: 

D. Cetin, M. Yayla, Y. Baykus, R. Deniz. Plasma urotensin-2 as a marker for menstrual irregularities in women: a clinical study. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 437-442.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog4676.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I3/437

[1] K. Uzel, I. Lakhno. PCR positivity and D-dimer levels in pregnant women with COVID-19[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 638-644.
[2] L. Roncati, M. Vadalà, C. Laurino, B. Palmieri. Multiple chemical sensitivity (MCS): women's health issue[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 629-631.
[3] P. Okrzymowska, M. Kurtys, N. Smolarek, M. Kurzaj, R. Slopien, K. Rozek-Piechura. Lung ventilation and the strength of the respiratory muscles of women in the third trimester of pregnancy in the aspect of physical activity[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(3): 324-328.
[4] A. A. Rouzi, R. Alamoudi, J. Turkistani, N. Almansouri, S. Alkafy, N. Alsinani, A. Wazzan. Miscarriage perceptions and experiences among Saudi women[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 208-214.
[5] T.-H. Kim, E. S. Lee, H.-H. Lee, J.-M. Kim, Y.-S. Kim, B. Lee. Vaginal health: insights, views, and attitudes (VIVA). Results from a survey in South Korea[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 938-942.
[6] O. OguztÁrk, N. Sagsoz. Personality profile in menopausal women[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 580-582.
[7] J.H. Check, C. Dietterich, J.K. Choe. Effect of hysteroscopic lysis of intrauterine adhesions in menstruating women on subsequent late proliferative phase endometrial thickness[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 375-376.
[8] S. Mattar, A. Nassar, L. Ghulmiyyah, S. Haddad, H. Tamim, E. Hobeika. Factors that affect women's choice of their obstetrician and gynecologist: a survey of Lebanese women[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 408-412.
[9] J. Wang, T. Jiang, X. Zhu, G. Tian. Femur length in normal fetuses and the correlation between crown-rump length and gestational age at 11-14 weeks in a Chinese Han population: a preliminary study[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 191-194.
[10] Y. Zheng, G. Niu, H. Zhang, W. Lu, Z. Liu. Estrogen replacement therapy is not a recommended therapy for postmenopausal women with coronary heart disease: a meta-analysis[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 219-226.
[11] O.B. Poli-Neto, P.S. Silva, T. Mangetti Gonçalvez, M.M. Máximo, J.C. Rosa-e-Silva, F.J. Candido-dos-Reis, A.A. Nogueira. Hormone therapy is not associated to pain thresholds in healthy postmenopausal women[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(1): 66-71.
[12] L.E. Prado Correia, B.C. de Almeida, E. Chada Baracat, I. Silva, J.M. Soares Júnior, C.E. Bonduki, M. Abi Haidar. Efficacy and effects of transdermal hormone therapy in postmenopausal women[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(5): 735-740.
[13] M. Li, L. Riming, W. Zhe, W. Hong, H. Xiaofei, C. Lina, Z. Zhengfang, W. Xuebo, W. Ning, S. Chengming, H. Qing-qing, L. Hailiang, W. Hui. Non-invasive prenatal screening for chromosome 21, 18, and 13 aneuploidies in a mixed risk factors pregnancy population[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(4): 523-528.
[14] S. Aslam, D. Al-Jaroudi. Women's involvement with the decision of caesarean section and their degree of satisfaction[J]. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(1): 88-92.
[15] M.N. Kenyon. Comparison between autonomic nervous activity of women in the sitting and supine position on the first postpartum day[J]. Clinical and Experimental Obstetrics & Gynecology, 2017, 44(6): 888-891.
No Suggested Reading articles found!