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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (3): 479-481    DOI: 10.12891/ceog4663.2019
Case Report Previous articles | Next articles
Bilateral pulmonary agenesis diagnosed in the 13 th week of gestation - a case report and literature review
T. Mihailovic1, B. Kuanova2, 3, M. Terzic2, 3, 4, *(), S. Terzic3, N. Arsenovic5
1Ultramedica Clinic, American Medical Academy, Belgrade, Serbia
2National Research Center of Mother and Child Health, University Medical Center, Astana, Kazakhstan
3Department of Medicine, Nazarbayev University, School of Medicine, Astana, Kazakhstan
4Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA
5Department of Cellular Pathology, PathLinks Pathology Services, Lincoln County Hospital, Lincoln, Uniyed Kingdom
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Bilateral pulmonary agenesis (BPA) is a rare congenital lung malformation incompatible with extra-uterine life, diagnosed by various prenatal imaging modalities in the second and third trimesters. Essentials for diagnosis are complete absence of lungs and bronchi and no pulmonary vascular supply. In the present case, both convex and vaginal ultrasound scan performed at 13th GW revealed an anechoic content in the entire fetal thorax with no evidence of pericardial effusion, fetal heart diseases, or any other accompanying congenital malformations. On three-vessel view (3VV), bifurcation of pulmonary artery could not be identified, which confirmed the diagnosis of BPA. In conclusion, clinical importance of combining the up-to-date technological tools and clinical expertise in establishing the diagnosis as early as in the first trimester allows the clinicians to terminate the pregnancy with the lowest incidence rate of eventual complications related to the procedure. According to the literature data, this is the first and therefore unique case of BPA diagnosed in the 13th week of gestation.

Key words:  Bilateral pulmonary agenesis      Bilateral lung agenesis      Lung aplasia      Ultrasound scan      First trimester     
Published:  10 June 2019     
*Corresponding Author(s):  M. TERZIC     E-mail:

Cite this article: 

T. Mihailovic, B. Kuanova, M. Terzic, S. Terzic, N. Arsenovic. Bilateral pulmonary agenesis diagnosed in the 13 th week of gestation - a case report and literature review. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 479-481.

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