Please wait a minute...
Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (5): 709-712    DOI: 10.12891/ceog4608.2019
Original Research Previous articles | Next articles
Pregnancy success rate at recurrent implantation failure patients after hysteroscopic endometrial injury: preliminary study
E.G. Aydeniz1, *(), U. Sari1, T.U.K. Dilek2
1Acibadem Mehmet Ali Aydinlar University Atakent Hospital, Obstetrics and Gynecology Clinic, Infertility Section, Istanbul, Turkey
2Acibadem Mehmet Ali Aydinlar University School of Medicine, Department of Obstetrics&Gynecology, Istanbul, Turkey
Download:  PDF(555KB)  ( 202 ) Full text   ( 10 )
Export:  BibTeX | EndNote (RIS)      
Abstract  

Purpose of Investigation: To assess better implantation and pregnancy rates following endometrial injury in the presence of previous implantation failure, through a retrospective study in a tertiary University Clinic. The aim of this study is to assess improved embryo implantation after hysteroscopic fundal endometrial injury in repeated implantation failure in patients. Materials and Methods: Twenty-nine women who had recurrent implantation failure participated in the study. They had three or more implantation failures with good quality embryo. Anti-Mullerian hormone (AMH) levels, age, antral follicle count, body mass index, and FSH levels were collected. Frozen/thawed embryos (FTE) were transferred in all subjects. Before embryo transfer the authors performed hysteroscopic endometrial injury by micro cold knife. Results: Median age was 38.62 ± 2.47 years in the study. AMH levels changed between 0.35 and 3.8 ng/ml. The pregnancy rate following hysteroscopy: 17 (58,6%) were pregnant and 12 of 29 subjects did not become pregnant. The women who became pregnant following hysteroscopy were younger and had a higher antral follicle count than the non-pregnant women (p = 0.030 and p = 0.0017 respectively; p < 0.05). Conclusion: The endometrial injury before frozen-thawed embryo transfer had a positive effect on patients who had previous recurrent implantation failure.

Key words:  Recurrent implantation failure      In-vitro fertilization      Infertility      Local endometrial injury      Clinical pregnancy rate     
Published:  10 October 2019     
*Corresponding Author(s):  E.G. AYDENIZ     E-mail:  gynelifaygun@gmail.com

Cite this article: 

E.G. Aydeniz, U. Sari, T.U.K. Dilek. Pregnancy success rate at recurrent implantation failure patients after hysteroscopic endometrial injury: preliminary study. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 709-712.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog4608.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I5/709

[1] A. Yaylalı, M. Bakacak, Z. Bakacak, F. Tolun. An investigation of the effects on follicular-embryonal development and pregnancy outcomes of serum and follicular fluid ischemia-modified albumin in cases of unexplained infertility receiving in vitro fertilization treatment[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 835-839.
[2] I. Thanaboonyawat, P. Chera-aree, S. Petyim, R. Choavaratana, P. Laokirkkiat. The effect of three-month topical testosterone gel application on semen quality in men with oligozoospermia and low serum testosterone levels[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 875-881.
[3] K. Okuno, K. Kitaya, N. Kim, K. Yamaguchi, H. Matsubayashi, T. Ishikawa. Case report of successful live birth in an infertile couple with male idiopathic hypogonadotropic hypogonadism/azoospermia and atypical polypoid adenomyoma of the uterus[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(6): 972-973.
[4] M. Elmahdy, I. Elfourtia, H. Maghraby. Office hysteroscopy in cases of recurrent implantation failure; Do or not to do[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(5): 723-728.
[5] B.G. Kadioglu, B. Gundogdu, N. Kurt, A. Ozbek Bilgin, H. Suleyman, Z. Suleyman. The effect of rhodiola rosea root extract on stress-induced ovarian damage, infertility and reproductive disorders in female rats[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(4): 530-536.
[6] S. J. Knight, A. D. Smith, H. Kim, A. C. Collier. Human placental suppressors of cytokine signalling (SOCS) and inflammatory cytokines are dysregulated in assisted reproduction, advanced maternal age and pre-term birth[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(2): 277-286.
[7] Hue HJ, Kim SK, Choi JY, Suh DH, Kim KD, No JH, Lee JR, Jee BC, Kim YB, Jeon HW. Previous ovarian surgery increases the risk of tubal factor infertility[J]. Clinical and Experimental Obstetrics & Gynecology, 2020, 47(1): 84-88.
[8] M. Minase, T. Miyamoto, N. Hayashi, G. Minase, K. Nishiwaki, K. Sengoku. A patient with a didelphys vaginal septum and infertility diagnosed by laparoscopy and magnetic resonance imaging[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(6): 988-989.
[9] J. Jeong, J. Yang, Y. J. Song, Y. J. Na, H. G. Kim. A case report of acute ovarian cyst torsion by female adnexal tumor of probable Wölffian origin[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(5): 824-827.
[10] K. Kitaya, Y. Takaya, R. Nishiyama, K. Yamaguchi, H. Matsubayashi, T. Takeuchi, S. Mizuta, T. Ishikawa. Myoinositol supplementation on intracytoplasmic sperm injection outcome in Japanese infertile polycystic ovarian syndrome women with non-obese less-androgenic phenotype: a prospective controlled observational study[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 549-552.
[11] H. Kwon, J.E. Shin, H. Kim. A novel treatment of severe dysmenorrhea due to adenomyosis: a case series of 3 infertile patients treated with dopamine agonist and in vitro fertilization-embryo transfer resulting in successful pregnancy[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(4): 637-640.
[12] P. Fuchs, I. Czech, A. Fuchs, J. Sikora. Use of neutral argon plasma in the treatment of endometriosis initial findings[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 434-436.
[13] J.H. Check, J. Liss, D. Check. The beneficial effect of luteal phase support on pregnancy rates in women with unexplained infertility[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(3): 447-449.
[14] I. Rudic Biljic-Erski, M. Vasiljevic, S. Rakic, S. Mihajlovic, O. D. Smiljkovic. The impact of hysteroscopic myomectomy on fertility and pregnancy outcomes of infertile women according characteristics of submucous fibroids[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 235-240.
[15] Chunjuan Shen, Liping Wang, Xiaojie Wu, Shuhui Mao, Chunxia Fang. The relationship between vitamin D and IVF: a systematic review and meta-analysis[J]. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(1): 12-15.
[1] Eli M. Roth, Michael H. Davidson. PCSK9 Inhibitors: Mechanism of Action, Efficacy, and Safety[J]. Reviews in Cardiovascular Medicine, 2018, 19(S1): 31 -46 .
[2] Sandeep K. Krishnan, Norman E. Lepor. Acute and Chronic Cardiovascular Effects of Hyperkalemia: New Insights Into Prevention and Clinical Management[J]. Reviews in Cardiovascular Medicine, 2016, 17(S1): 9 -21 .
[3] Ibrahim Sidiqi, Patrick Alexander. Current Advances in Endovascular Therapy for Infrapopliteal Artery Disease[J]. Reviews in Cardiovascular Medicine, 2015, 16(1): 36 -50 .
[4] Peter Shalit. Management of Dyslipidemia in Patients With Human Immunodeficiency Virus[J]. Reviews in Cardiovascular Medicine, 2014, 15(S1): 38 -46 .
[5] Sophie Mavrogeni, Fabrizio Cantini, Gerald M. Pohost. Systemic Vasculitis: An Underestimated Cause of Heart Failure—Assessment by Cardiovascular Magnetic Resonance[J]. Reviews in Cardiovascular Medicine, 2013, 14(1): 49 -55 .
[6] George L. Smith. Appropriate Use Criteria: The Gold Standard, or a Mechanism for the Derogation of Clinical Judgment?[J]. Reviews in Cardiovascular Medicine, 2011, 12(2): 105 .
[7] Prabhjot Singh Nijjar, Anoop Parameswaran, Aman M. Amanullah. Evaluation of Anomalous Aortic Origins of the Coronaries by 64-Slice Cardiac Computed Tomography[J]. Reviews in Cardiovascular Medicine, 2007, 8(3): 175 -181 .
[8] . SELF-ASSESSMENT POST-TEST[J]. Reviews in Cardiovascular Medicine, 2006, 7(S2): 51 -52 .
[9] Alice K. Jacobs. Gender Differences in Coronary Revascularization: Does Age Make a Difference?[J]. Reviews in Cardiovascular Medicine, 2004, 5(1): 68 -70 .
[10] Jeffrey W. Moses, Stephane Carlier, Issam Moussa. Lesion Preparation Prior to Stenting[J]. Reviews in Cardiovascular Medicine, 2004, 5(S2): 16 -21 .