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Clinical and Experimental Obstetrics & Gynecology  2019, Vol. 46 Issue (2): 331-332    DOI: 10.12891/ceog4576.2019
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Successful ongoing pregnancy following cryopreserved-thawed blastocyst transfer in an infertile Kallmann syndrome woman with balanced reciprocal translocation: a case report
R. Nishiyama1, K. Kitaya1, *(), Y. Takaya1, K. Yamaguchi1, N. Kim1, H. Matsubayashi1, T. Ishikawa1
1Reproduction Clinic Osaka, Osaka, Japan
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Abstract  

Kallmann syndrome (KS) is a genetic disorder characterized by hypogonadotropic hypogonadism, anosmia, and infertility, occurring in approximately one in 50, 000 women. Here the authors present a unique case of successful ongoing pregnancy in an infertile KS woman with balanced reciprocal translocation [t(12;18)(q22;q21.1)]. The patient had a history of one sporadic miscarriage and low level of serum anti-Müllerian hormone, basal follicular stimulating hormone, luteinizing hormone, and estradiol concentration. She showed a good response to ovulation induction using human menopausal gonadotropin and chorionic gonadotropin and conceived in an in vitro fertilization and cryopreserved-thawed blastocyst transfer cycle.

Key words:  Anti-Müllerian hormone      Balanced reciprocal translocation      Kallmann syndrome     
Published:  10 April 2019     
*Corresponding Author(s):  K. KITAYA     E-mail:  kitaya@koto.kpu-m.ac.jp

Cite this article: 

R. Nishiyama, K. Kitaya, Y. Takaya, K. Yamaguchi, N. Kim, H. Matsubayashi, T. Ishikawa. Successful ongoing pregnancy following cryopreserved-thawed blastocyst transfer in an infertile Kallmann syndrome woman with balanced reciprocal translocation: a case report. Clinical and Experimental Obstetrics & Gynecology, 2019, 46(2): 331-332.

URL: 

https://ceog.imrpress.com/EN/10.12891/ceog4576.2019     OR     https://ceog.imrpress.com/EN/Y2019/V46/I2/331

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