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Screening for group B hemolytic streptococcal infection in pregnancy in a low-resourced country |
B. Bassaw1, *( ), R. Romeo-Bassey2, A. Jaggat3, M. Manjunath2, S. Perkins2, S. Khan4 |
1 The University of the West Indies, St. Augustine Campus, Trinidad 2Port-of-Spain General Hospital, Port-of-Spain, Trinidad 3Westshore Medical Hospital, Port-of-Spain, Trinidad 4San Fernando General Hospital, San Fernando, Trinidad |
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Abstract Objectives: The objectives of this study conducted in a low-resourced country were to determine the feasibility and acceptability among pregnant women of universal screening for group B streptococcus (GBS), the prevalence of GBS, to calculate the risk of vertical transmission, and to study the neonatal outcome of early onset group B streptococcus disease (EOGBSD). Materials and Methods: All pregnant women between 35-37 weeks of gestation who attended the Port-of-Spain General Hospital during a six-month interval were enrolled in a study involving universal screening for group B streptococcus from vaginal and ano-rectal swabs. After appropriate laboratory preparation, inspection of the plate for GBS was performed. Patients found to be GBS screen-positive received intrapartum antibiotic prophylaxis (IAP). Results: Among the 420 eligible patients, 341 women (81.2%) agreed to participate. A total of 52 maternities (15.2%) were confirmed as GBS screen-positive. The highest rate of positive results were observed in Afro-Caribbean women, although this difference was not statistically significant (p > 0.05). Intrapartum antibiotic prophylaxis (IAP) was administered to 37 patients (71.1%). Conclusion: This study reveals that despite the relatively low prevalence rate of GBS, a policy of universal screening and IAP in low-resourced countries, it is possible to address the major burden of EOGBSD.
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Published: 10 February 2019
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*Corresponding Author(s):
B. BASSAW
E-mail: bharath.bassaw@sta.uwi.edu
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