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| The effects of fetal gender on pregnancy induced hypertension in twin pregnancy |
Ze Chen1, Xiaoping Lei2, Yongjun Zhang3, *( ) |
1 Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
2 Department of Neonatology, Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan, China
3 MOE and Shanghai Key Laboratory of Children's Environmental Health, Shanghai, China |
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Abstract
Purpose of investigation: To determine whether pregnancy induced hypertension (PIH) is associated with fetal gender. Materials and Methods: The authors reviewed the records of 26,026 pairs of twins from the US 1995-2004 Matched Multiple Birth Dataset (the largest multiple dataset available for multiple births). Logistic regression model was applied to estimate the odds ratio (OR) between different sex groups of twins. Results: The authors found that compared with male-male group (7.60%), the incidence of PIH in femalefemale and female-male groups are 8.25% (adjusted odds ratio (aOR) 1.10, 95% confidence interval 1.06-1.13 and 8.14% (aOR 1.08, 95% confidence interval (CI) 1.05-1.11), respectively. Comparably, the incidence of eclampsia has no significant difference among three groups. Conclusion: The present finding confirms that the fetal gender has partially influenced on the incidence of PIH, while having no effects on eclampsia.
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Published: 10 June 2018
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*Corresponding Author(s):
YONGJUN ZHANG
E-mail: zhangyongjun@sjtu.edu.cn
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2018, Vol. 45 
