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Clinical and Experimental Obstetrics & Gynecology  2018, Vol. 45 Issue (1): 126-128    DOI: 10.12891/ceog3952.2018
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Exacerbation of neurofibromatosis and adverse pregnancy outcome. A case report and review of the literature
M. Matalliotakis1, *(), A. Velegrakis1, A. Laliotis3, E. Niraki1, A. Trivli2
1 Department of Gynecology and Obstetrics, Venizeleio & Pananio General Hospital of Heraklion, Heraklion, Greece
2 Department of Ophthalmology, Konstantopouleio-Patission General Hospital of N.Ionia, Athens, Greece
3 Department of Surgery, St George's University Hospital NHS Foundation Trust Blackshaw Road, Tooting London, United Kingdom
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Abstract  
Neurofibromatosis type 1 (NF-1) is a condition which has markedly variable clinical expressions. During pregnancy the manifestations of the disorder are exacerbated, and as a result, mild to severe maternal and fetal complications may appear. A case of neurofibromatosis affected by pregnancy is presented. The mother presented with high arterial blood pressure, renal insufficiency, and visual impairment. At the same time the baby was born with growth restriction and cerebellar haemorrhage. Altogether, NF1 is associated with increased maternal and fetal morbidity in pregnancy but not with increased maternal mortality.
Key words:  Neurofibromatosis      Obstetric complication      Visual impairment     
Published:  10 February 2018     
*Corresponding Author(s):  M. MATALLIOTAKIS     E-mail:  mihalismat@hotmail.com

Cite this article: 

M. Matalliotakis, A. Velegrakis, A. Laliotis, E. Niraki, A. Trivli. Exacerbation of neurofibromatosis and adverse pregnancy outcome. A case report and review of the literature. Clinical and Experimental Obstetrics & Gynecology, 2018, 45(1): 126-128.

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https://ceog.imrpress.com/EN/10.12891/ceog3952.2018     OR     https://ceog.imrpress.com/EN/Y2018/V45/I1/126

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